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Catalog Number:
37983
CAS Number:
65277-42-1
Ketoconazole
Grade:
Meets USP Specification
Purity:
98 - 102% (Assay on dried basis)
Synonym(s):
(+/-)-cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine
Hazmat
Documents
$18.50 /25G
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Product Information
Synonyms
(+/-)-cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine
CAS Number
65277-42-1
Purity
98 - 102% (Assay on dried basis)
Grade
Meets USP Specification
Molecular Formula
C26H28Cl2N4O4
Molecular Weight
0
MDL Number
MFCD00058579
PubChem ID
3823
Melting Point
150 - 155 °C (Lit.)
Appearance
White to almost white powder
Optical Rotation
[a]D20 = -1 to 1 ° (C=40 mg/mL in Methanol)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(+/-)-cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine
CAS Number
65277-42-1
Purity
98 - 102% (Assay on dried basis)
Grade
Meets USP Specification
Molecular Formula
C26H28Cl2N4O4
Molecular Weight
0
MDL Number
MFCD00058579
PubChem ID
3823
Melting Point
150 - 155 °C (Lit.)
Appearance
White to almost white powder
Optical Rotation
[a]D20 = -1 to 1 ° (C=40 mg/mL in Methanol)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ketoconazole is widely utilized in research focused on:

  • Antifungal Treatments: Commonly used in dermatology, ketoconazole is effective against various fungal infections, such as athlete's foot and ringworm, providing relief and promoting skin health.
  • Shampoos for Scalp Conditions: Incorporated into medicated shampoos, it helps treat dandruff and seborrheic dermatitis by reducing fungal growth on the scalp, improving overall hair and scalp condition.
  • Hormonal Imbalance Management: In endocrinology, ketoconazole is used to manage conditions like Cushing's syndrome by inhibiting cortisol production, assisting patients in regulating hormone levels.
  • Research in Drug Development: As a model compound, it aids in the study of antifungal mechanisms and resistance, helping researchers develop more effective antifungal agents.
  • Veterinary Medicine: Utilized in treating fungal infections in animals, ketoconazole supports veterinary professionals in managing pet health, particularly for skin and systemic fungal issues.

Citations