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Catalog Number:
37965
CAS Number:
89396-94-1
Imidapril hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
(4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylicacid hydrochloride, Novaloc hydrochloride
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$281.42 /25MG
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Product Information

Imidapril hydrochloride is a potent angiotensin-converting enzyme (ACE) inhibitor widely utilized in the treatment of hypertension and heart failure. This compound works by relaxing blood vessels, thereby reducing blood pressure and improving blood flow, making it essential in cardiovascular therapy. Its unique structure allows for effective inhibition of the ACE enzyme, leading to decreased production of angiotensin II, a peptide that constricts blood vessels. This mechanism not only aids in managing high blood pressure but also provides protective benefits for the heart and kidneys, particularly in patients with diabetes or chronic kidney disease.

In addition to its therapeutic applications, Imidapril hydrochloride is also valuable in research settings, where it serves as a model compound for studying the pharmacological effects of ACE inhibitors. Its effectiveness and safety profile make it a preferred choice among healthcare professionals for long-term management of cardiovascular conditions. Researchers and industry professionals appreciate its ability to enhance patient outcomes while minimizing side effects, setting it apart from other compounds in the same class.

Synonyms
(4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylicacid hydrochloride, Novaloc hydrochloride
CAS Number
89396-94-1
Purity
≥ 98% (HPLC)
Molecular Formula
C20H27N3O6·HCl
Molecular Weight
441.91
MDL Number
MFCD00923828
PubChem ID
21989737
Melting Point
205 - 207 °C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -65 to -69 ° (C=1, MeOH)
Conditions
Store at < 0 °C
General Information
Synonyms
(4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylicacid hydrochloride, Novaloc hydrochloride
CAS Number
89396-94-1
Purity
≥ 98% (HPLC)
Molecular Formula
C20H27N3O6·HCl
Molecular Weight
441.91
MDL Number
MFCD00923828
PubChem ID
21989737
Melting Point
205 - 207 °C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -65 to -69 ° (C=1, MeOH)
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Imidapril hydrochloride is widely utilized in research focused on:

  • Hypertension Treatment: This compound is primarily used in the pharmaceutical industry to manage high blood pressure, providing an effective option for patients who require long-term medication.
  • Heart Failure Management: It plays a critical role in treating heart failure by improving cardiac output and reducing the workload on the heart, making it essential for cardiologists.
  • Research on Angiotensin-Converting Enzyme (ACE) Inhibitors: Imidapril hydrochloride is a valuable tool in studies investigating the mechanisms of ACE inhibitors, aiding researchers in developing new cardiovascular therapies.
  • Combination Therapies: This compound is often used in combination with other antihypertensive agents, enhancing treatment efficacy and providing tailored solutions for patients with complex health needs.
  • Pharmacokinetic Studies: Researchers utilize imidapril hydrochloride in pharmacokinetic studies to understand its absorption, distribution, metabolism, and excretion, which is crucial for drug development and safety assessments.

Citations