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Catalog Number:
37938
CAS Number:
65646-68-6
all-trans-N-(4-Hydroxyphenyl)retinamide
Purity:
≥ 98% (HPLC)
Synonym(s):
4-HPR, Retinoic acid p-hydroxyanilide
Documents
$160.34 /10MG
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Product Information

All-trans-N-(4-Hydroxyphenyl)retinamide, also known as Tretinoin or 4-Hydroxyphenylretinamide, is a synthetic derivative of vitamin A that has garnered significant attention in dermatological and pharmaceutical applications. This compound is particularly valued for its role in skin care, where it is utilized for its potent anti-aging and acne treatment properties. Its ability to promote cell turnover and enhance skin texture makes it a popular choice among researchers and industry professionals focused on developing effective topical formulations. Additionally, all-trans-N-(4-Hydroxyphenyl)retinamide has been studied for its potential in cancer research, particularly in the modulation of cellular differentiation and apoptosis, offering promising avenues for therapeutic interventions.

The compound's unique structure allows it to penetrate the skin effectively, delivering targeted benefits without the irritation commonly associated with other retinoids. This makes it an ideal candidate for sensitive skin formulations. Furthermore, its stability and efficacy in various formulations, including creams and serums, enhance its appeal in cosmetic and pharmaceutical industries. Researchers and formulators can leverage its properties to create innovative products that meet the growing demand for effective skin care solutions.

Synonyms
4-HPR, Retinoic acid p-hydroxyanilide
CAS Number
65646-68-6
Purity
≥ 98% (HPLC)
Molecular Formula
C26H33NO2
Molecular Weight
391.56
MDL Number
MFCD00792674
PubChem ID
1744
Melting Point
170 - 174 ?C
Appearance
White to yellow to orange powder to crystal
Conditions
Store at < -20 °C
General Information
Synonyms
4-HPR, Retinoic acid p-hydroxyanilide
CAS Number
65646-68-6
Purity
≥ 98% (HPLC)
Molecular Formula
C26H33NO2
Molecular Weight
391.56
MDL Number
MFCD00792674
PubChem ID
1744
Melting Point
170 - 174 ?C
Appearance
White to yellow to orange powder to crystal
Conditions
Store at < -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

All-trans-N-(4-Hydroxyphenyl)retinamide is widely utilized in research focused on:

  • Dermatology: This compound is used in topical formulations for treating acne and photoaging due to its ability to regulate skin cell turnover and reduce inflammation.
  • Oncology: It has shown potential in cancer research, particularly in promoting apoptosis in certain cancer cells, making it a candidate for developing novel cancer therapies.
  • Ophthalmology: The compound is being studied for its protective effects on retinal cells, potentially aiding in the treatment of age-related macular degeneration and other retinal diseases.
  • Cosmetics: Its antioxidant properties make it a valuable ingredient in anti-aging products, helping to improve skin texture and reduce the appearance of fine lines.
  • Pharmaceuticals: The compound is explored for its role in modulating gene expression, which can lead to advancements in drug development for various diseases, including neurodegenerative disorders.

Citations