Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
37894
CAS Number:
78755-81-4
Flumazenil
Purity:
≥ 99% (GC)
Synonym(s):
Ro 15-1788
Documents
$91.74 /25MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Flumazenil is a potent benzodiazepine antagonist, primarily utilized in the medical field for reversing the effects of benzodiazepine sedation. This compound is particularly valuable in emergency medicine, where it is administered to counteract the sedative effects of benzodiazepines in cases of overdose or during procedures requiring rapid recovery from sedation. Its unique structure, characterized by the presence of a fluoro group and a carboxylate moiety, enhances its binding affinity to the GABA-A receptor, making it an effective choice for clinicians seeking to restore consciousness in patients.

In addition to its clinical applications, Flumazenil is also of interest in pharmacological research, where it serves as a tool for studying the mechanisms of benzodiazepine action and dependency. Researchers leverage its antagonistic properties to explore the pathways involved in anxiety and sleep disorders, providing insights that could lead to the development of novel therapeutic agents. With its specific action and rapid onset, Flumazenil stands out as a critical compound in both therapeutic and research settings.

Synonyms
Ro 15-1788
CAS Number
78755-81-4
Purity
≥ 99% (GC)
Molecular Formula
C15H14FN3O3
Molecular Weight
303.29
MDL Number
MFCD00242764
PubChem ID
3373
Melting Point
198 - 202 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Ro 15-1788
CAS Number
78755-81-4
Purity
≥ 99% (GC)
Molecular Formula
C15H14FN3O3
Molecular Weight
303.29
MDL Number
MFCD00242764
PubChem ID
3373
Melting Point
198 - 202 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Flumazenil is widely utilized in research focused on:

  • Reversal of Benzodiazepine Sedation: It is primarily used in medical settings to reverse the effects of benzodiazepines in patients who have overdosed or are experiencing prolonged sedation after surgery.
  • Diagnostic Tool: In emergency medicine, Flumazenil helps differentiate between benzodiazepine overdose and other causes of altered mental status, aiding in quicker diagnosis and treatment.
  • Research on Anxiety Disorders: Researchers use Flumazenil to study its effects on anxiety and depression, providing insights into the mechanisms of benzodiazepines and potential alternatives for treatment.
  • Pharmacological Studies: It serves as a valuable tool in pharmacology to investigate the interactions between benzodiazepines and their receptors, enhancing the understanding of drug efficacy and safety.
  • Postoperative Care: In surgical recovery, Flumazenil is administered to speed up the recovery process from anesthesia, allowing patients to regain consciousness and cognitive function more quickly.

Citations