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Catalog Number:
37825
CAS Number:
58-73-1
Diphenhydramine
Purity:
≥ 98% (Assay by titration, GC)
Synonym(s):
2-Diphenylmethoxy-N,N-dimethylethylamine, 2-(Benzhydryloxy)-N,N-dimethylethylamine
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Product Information

Diphenhydramine is a well-known antihistamine that is widely utilized in both pharmaceutical and research applications. Recognized for its effectiveness in alleviating allergy symptoms, it is commonly found in over-the-counter medications for hay fever, allergic rhinitis, and other allergic conditions. Beyond its primary use as an antihistamine, Diphenhydramine also possesses sedative properties, making it valuable in sleep aids and treatments for motion sickness. Its ability to cross the blood-brain barrier enhances its effectiveness in managing insomnia and anxiety-related disorders, providing a dual benefit for healthcare professionals and patients alike.

In research settings, Diphenhydramine is often employed in studies related to sleep pharmacology and the effects of antihistamines on cognitive function. Its unique profile allows researchers to explore its potential in various therapeutic areas, including neuropharmacology and psychopharmacology. With its established safety profile and versatility, Diphenhydramine remains a critical compound for both clinical and experimental applications, making it an essential addition to any pharmaceutical or research portfolio.

Synonyms
2-Diphenylmethoxy-N,N-dimethylethylamine, 2-(Benzhydryloxy)-N,N-dimethylethylamine
CAS Number
58-73-1
Purity
≥ 98% (Assay by titration, GC)
Molecular Formula
C17H21NO
Molecular Weight
255.36
MDL Number
MFCD00274173
PubChem ID
3100
Density
1.02
Appearance
White to yellow to green clear liquid
Refractive Index
1.55
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Diphenylmethoxy-N,N-dimethylethylamine, 2-(Benzhydryloxy)-N,N-dimethylethylamine
CAS Number
58-73-1
Purity
≥ 98% (Assay by titration, GC)
Molecular Formula
C17H21NO
Molecular Weight
255.36
MDL Number
MFCD00274173
PubChem ID
3100
Density
1.02
Appearance
White to yellow to green clear liquid
Refractive Index
1.55
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Diphenhydramine is widely utilized in research focused on:

  • Allergy Relief: Commonly found in over-the-counter medications, it effectively alleviates symptoms of hay fever and other allergic reactions, making it a go-to choice for consumers seeking quick relief.
  • Sleep Aid: Due to its sedative properties, it is often used in sleep medications, providing a non-prescription option for those struggling with insomnia.
  • Motion Sickness Prevention: It is effective in preventing nausea and dizziness associated with motion sickness, making it valuable for travelers and those prone to discomfort during transit.
  • Cold and Flu Treatment: As an antihistamine, it helps reduce symptoms like runny nose and sneezing, commonly included in cold and flu formulations to enhance patient comfort.
  • Research Applications: In scientific studies, it serves as a model compound for investigating antihistaminic effects and drug interactions, aiding researchers in developing new therapeutic agents.

Citations