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Catalog Number:
37822
CAS Number:
14484-47-0
Deflazacort
Purity:
≥ 98% (HPLC)
Synonym(s):
(11b,16b)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, Oxazacort
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Product Information

Deflazacort is a synthetic glucocorticoid with potent anti-inflammatory and immunosuppressive properties, making it a valuable compound in various medical applications. It is primarily used in the treatment of autoimmune disorders, such as rheumatoid arthritis and systemic lupus erythematosus, where it helps to reduce inflammation and modulate the immune response. Additionally, Deflazacort is effective in managing conditions like asthma and certain skin disorders, providing relief from symptoms while minimizing side effects compared to traditional corticosteroids.

Researchers and healthcare professionals appreciate Deflazacort for its unique profile, which includes a lower incidence of weight gain and other metabolic side effects, making it a preferred choice for long-term therapy. Its ability to enhance muscle strength and function in patients with chronic conditions further underscores its relevance in clinical settings. With its versatile applications and favorable safety profile, Deflazacort stands out as a significant therapeutic agent in modern medicine.

Synonyms
(11b,16b)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, Oxazacort
CAS Number
14484-47-0
Purity
≥ 98% (HPLC)
Molecular Formula
C25H31NO6
Molecular Weight
441.52
MDL Number
MFCD00866106
PubChem ID
26709
Melting Point
256 - 260 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = 63 - 74 ° (C=0.5 in CHCl3)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(11b,16b)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, Oxazacort
CAS Number
14484-47-0
Purity
≥ 98% (HPLC)
Molecular Formula
C25H31NO6
Molecular Weight
441.52
MDL Number
MFCD00866106
PubChem ID
26709
Melting Point
256 - 260 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = 63 - 74 ° (C=0.5 in CHCl3)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Deflazacort is widely utilized in research focused on:

  • Anti-inflammatory Treatments: Commonly prescribed for conditions like rheumatoid arthritis and asthma, it helps reduce inflammation and improve patient comfort.
  • Autoimmune Disorders: Effective in managing symptoms of autoimmune diseases, providing relief and improving quality of life for patients with conditions such as lupus and multiple sclerosis.
  • Organ Transplantation: Used as an immunosuppressant to prevent organ rejection, enhancing the success rates of transplants and improving patient outcomes.
  • Pediatric Applications: Beneficial in treating severe allergic reactions and certain types of cancer in children, offering a safer alternative with fewer side effects compared to other corticosteroids.
  • Dermatological Conditions: Applied in treating skin disorders like eczema and psoriasis, it helps alleviate symptoms and promote healing effectively.

Citations