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Catalog Number:
37802
CAS Number:
114977-28-5
Docetaxel
Purity:
97.8 - 102.0% (Assay on anhydrous and solvent free basis)
Synonym(s):
N-Debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol
Documents
$35.00 /100MG
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Product Information

Docetaxel is a potent chemotherapeutic agent widely recognized for its effectiveness in treating various cancers, including breast, lung, and prostate cancer. As a member of the taxane family, it functions by inhibiting cell division, thereby preventing the growth and spread of cancerous cells. This compound is particularly valued in oncology due to its ability to enhance the efficacy of other treatments and its unique mechanism of action, which stabilizes microtubules and disrupts normal mitotic processes.

In clinical settings, Docetaxel is often utilized in combination therapies, maximizing therapeutic outcomes while minimizing resistance. Its formulation as an injectable solution allows for controlled administration, making it a preferred choice among healthcare professionals. Additionally, ongoing research continues to explore its potential in treating other malignancies and its role in personalized medicine, highlighting its versatility and importance in modern cancer treatment protocols.

Synonyms
N-Debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol
CAS Number
114977-28-5
Purity
97.8 - 102.0% (Assay on anhydrous and solvent free basis)
Molecular Formula
C43H53NO14
Molecular Weight
807.89
MDL Number
MFCD00800737
PubChem ID
3143
Melting Point
188 °C (dec.)
Appearance
White or almost white crystalline powder
Optical Rotation
[a]D20 = -45 to -35 ° (on as-is basis)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N-Debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol
CAS Number
114977-28-5
Purity
97.8 - 102.0% (Assay on anhydrous and solvent free basis)
Molecular Formula
C43H53NO14
Molecular Weight
807.89
MDL Number
MFCD00800737
PubChem ID
3143
Melting Point
188 °C (dec.)
Appearance
White or almost white crystalline powder
Optical Rotation
[a]D20 = -45 to -35 ° (on as-is basis)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Docetaxel is widely utilized in research focused on:

  • Cancer Treatment: Primarily used as a chemotherapy drug for treating various types of cancer, including breast, lung, and prostate cancer. Its effectiveness in disrupting cancer cell division makes it a cornerstone in oncological therapies.
  • Combination Therapies: Often combined with other medications to enhance treatment efficacy. For example, it can be paired with corticosteroids to reduce side effects and improve patient outcomes.
  • Pharmaceutical Research: Used in the development of new formulations and drug delivery systems, allowing researchers to explore innovative ways to improve drug absorption and reduce toxicity.
  • Clinical Trials: Frequently involved in clinical studies aimed at assessing new treatment regimens or combinations, providing valuable data that can lead to improved cancer therapies.
  • Biotechnology Applications: Employed in the production of biosimilars, which are biologic medical products highly similar to already approved reference products, helping to expand treatment options for patients.

Citations