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Catalog Number:
37793
CAS Number:
100643-71-8
Desloratadine
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2,b]pyridine
Documents
$42.46 /100MG
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Product Information

Desloratadine is a potent, non-sedating antihistamine widely recognized for its effectiveness in alleviating allergy symptoms such as sneezing, runny nose, and itchy eyes. This compound is particularly valued in the pharmaceutical industry for its ability to provide long-lasting relief from allergic reactions without causing drowsiness, making it an ideal choice for individuals seeking to maintain their daily activities without interruption. Desloratadine operates by selectively blocking peripheral histamine H1 receptors, thus reducing the physiological effects of histamine release during allergic responses.

In addition to its primary use in treating seasonal allergic rhinitis, Desloratadine is also employed in managing chronic idiopathic urticaria, providing relief from hives and associated discomfort. Its favorable pharmacokinetic profile allows for once-daily dosing, enhancing patient compliance. Researchers and healthcare professionals appreciate Desloratadine for its minimal side effects compared to first-generation antihistamines, making it a preferred option in allergy management. With its proven efficacy and safety, Desloratadine continues to be a vital component in modern allergy treatment regimens.

Synonyms
8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2,b]pyridine
CAS Number
100643-71-8
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C19H19ClN2
Molecular Weight
310.83
MDL Number
MFCD00871949
PubChem ID
124087
Melting Point
155 - 159 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2,b]pyridine
CAS Number
100643-71-8
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C19H19ClN2
Molecular Weight
310.83
MDL Number
MFCD00871949
PubChem ID
124087
Melting Point
155 - 159 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Desloratadine is widely utilized in research focused on:

  • Allergy Relief: Commonly used in the pharmaceutical industry, it serves as an effective antihistamine for treating allergic rhinitis and chronic urticaria, providing relief from symptoms like sneezing and itching.
  • Clinical Research: Frequently studied in clinical trials to evaluate its efficacy and safety compared to other antihistamines, helping to establish best practices in allergy management.
  • Pediatric Applications: Formulated for children, it offers a non-sedating option for allergy treatment, addressing the specific needs of younger patients and their caregivers.
  • Combination Therapies: Investigated for use in combination with other medications to enhance therapeutic outcomes in patients with complex allergy profiles, improving overall patient care.
  • Pharmacogenomics: Explored in studies assessing how genetic variations affect individual responses to antihistamines, paving the way for personalized medicine in allergy treatment.

Citations