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Catalog Number:
37771
CAS Number:
147-24-0
Diphenhydramine hydrochloride
Grade:
meets USP specification
Purity:
98 - 102% (Assay, on dry basis)
Synonym(s):
2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride, 2-(Benzhydryloxy)-N,N-dimethylethylamine hydrochloride
Documents
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Product Information

Diphenhydramine hydrochloride is a well-known antihistamine that is widely utilized in both pharmaceutical and research applications. This compound is primarily recognized for its effectiveness in alleviating allergy symptoms, such as sneezing, runny nose, and itching. Additionally, it is often employed as a sleep aid due to its sedative properties, making it a popular choice for individuals seeking relief from insomnia. In the pharmaceutical industry, Diphenhydramine hydrochloride serves as a key ingredient in various over-the-counter medications, enhancing their efficacy in treating allergic reactions and motion sickness. Its versatility extends to research settings, where it is used in studies related to sleep disorders and the effects of antihistamines on cognitive function.

The unique properties of Diphenhydramine hydrochloride, including its ability to cross the blood-brain barrier, allow it to exert central nervous system effects, which can be beneficial in both therapeutic and experimental contexts. Researchers appreciate its well-documented safety profile and the extensive body of literature supporting its use, making it a reliable choice for various applications. Whether in clinical settings or laboratory research, Diphenhydramine hydrochloride continues to be a valuable compound for professionals seeking effective solutions in allergy management and sleep studies.

Synonyms
2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride, 2-(Benzhydryloxy)-N,N-dimethylethylamine hydrochloride
CAS Number
147-24-0
Purity
98 - 102% (Assay, on dry basis)
Grade
meets USP specification
Molecular Formula
C17H21NO·HCl
Molecular Weight
291.82
MDL Number
MFCD00012479
PubChem ID
8980
Melting Point
168 - 172 °C
Appearance
White crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride, 2-(Benzhydryloxy)-N,N-dimethylethylamine hydrochloride
CAS Number
147-24-0
Purity
98 - 102% (Assay, on dry basis)
Grade
meets USP specification
Molecular Formula
C17H21NO·HCl
Molecular Weight
291.82
MDL Number
MFCD00012479
PubChem ID
8980
Melting Point
168 - 172 °C
Appearance
White crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Diphenhydramine hydrochloride is widely utilized in research focused on:

  • Allergy Relief: Commonly used in over-the-counter medications, it effectively alleviates symptoms of hay fever and other allergic reactions, making it a staple in the pharmaceutical industry.
  • Sleep Aid: Due to its sedative properties, it is often included in sleep medications, providing a non-prescription option for individuals struggling with insomnia.
  • Motion Sickness Prevention: Frequently used in travel medications, it helps prevent nausea and vomiting associated with motion sickness, benefiting travelers and those prone to discomfort.
  • Cold and Flu Treatment: It is a common ingredient in combination cold medications, helping to relieve symptoms such as runny nose and sneezing, thus enhancing patient comfort during illness.
  • Research Applications: In scientific studies, it serves as a model compound for investigating antihistaminic effects and understanding drug interactions, aiding researchers in developing new therapeutic agents.

Citations