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Catalog Number:
37759
CAS Number:
470-37-1
Cinobufagine
Purity:
≥ 98% (HPLC)
Synonym(s):
14,15ß-Epoxy-3ß,16ß-dihydroxy-5ß,20(22)-bufadienolide 16-acetate, Cinobufagin
Hazmat
Documents
$362.54 /25MG
Pack Size Availability Price
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Product Information

Cinobufagine is a naturally occurring compound derived from the skin of toads, known for its unique pharmacological properties. This pentacyclic compound has garnered attention in the fields of pharmacology and medicinal chemistry due to its potential therapeutic applications. Its structure features a complex arrangement of rings and functional groups, which contribute to its biological activity. Researchers have explored its use in traditional medicine, particularly in East Asian cultures, where it has been utilized for its purported cardioprotective and anti-inflammatory effects.

In modern applications, Cinobufagine is being investigated for its potential in treating various cardiovascular conditions and as an adjunct in cancer therapies. Its ability to modulate cellular signaling pathways makes it a candidate for further research in drug development. The compound's unique properties set it apart from similar agents, offering promising avenues for innovation in therapeutic strategies. As interest in natural compounds grows, Cinobufagine stands out as a valuable resource for researchers and industry professionals seeking effective solutions in health and medicine.

Synonyms
14,15ß-Epoxy-3ß,16ß-dihydroxy-5ß,20(22)-bufadienolide 16-acetate, Cinobufagin
CAS Number
470-37-1
Purity
≥ 98% (HPLC)
Molecular Formula
C26H34O6
Molecular Weight
442.55
MDL Number
MFCD00058625
PubChem ID
633349
Melting Point
213 - 217 ?C
Appearance
White to light yellow powder to crystal
Optical Rotation
[a]20D = -3 to -4 ° (C=1 in CHCl3
Conditions
Store at 2 - 8 °C
General Information
Synonyms
14,15ß-Epoxy-3ß,16ß-dihydroxy-5ß,20(22)-bufadienolide 16-acetate, Cinobufagin
CAS Number
470-37-1
Purity
≥ 98% (HPLC)
Molecular Formula
C26H34O6
Molecular Weight
442.55
MDL Number
MFCD00058625
PubChem ID
633349
Melting Point
213 - 217 ?C
Appearance
White to light yellow powder to crystal
Optical Rotation
[a]20D = -3 to -4 ° (C=1 in CHCl3
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Cinobufagine is widely utilized in research focused on:

  • Cardiovascular Health: This compound has shown potential in studies related to heart function and blood pressure regulation, making it a candidate for developing treatments for cardiovascular diseases.
  • Anti-cancer Research: Researchers are exploring its effects on cancer cells, with some studies indicating that it may inhibit tumor growth, presenting a promising avenue for oncology.
  • Neuroprotective Applications: Cinobufagine is being investigated for its neuroprotective properties, which could lead to advancements in treating neurodegenerative disorders such as Alzheimer's and Parkinson's disease.
  • Traditional Medicine: Historically used in traditional Chinese medicine, it is gaining attention for its potential therapeutic benefits, which may provide insights into alternative treatment modalities.
  • Pharmacological Studies: Its unique chemical structure allows for various pharmacological investigations, aiding in the development of new drugs and understanding their mechanisms of action.

Citations