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Catalog Number:
37747
CAS Number:
32222-06-3
Calcitriol
Purity:
≥ 97% (HPLC)
Synonym(s):
1a,25-Dihydroxyvitamin D3, 1,25-Dihydroxycholecalciferol
Hazmat
Documents
$932.20 /1MG
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Product Information

Calcitriol, the active form of Vitamin D3, is a crucial compound in the regulation of calcium and phosphate metabolism in the body. This biologically active metabolite is widely recognized for its role in promoting bone health and is utilized in the treatment of various conditions such as osteoporosis, rickets, and certain types of hypoparathyroidism. Its unique ability to enhance intestinal absorption of calcium makes it invaluable in clinical settings, particularly for patients with deficiencies or disorders affecting calcium metabolism.

In addition to its therapeutic applications, Calcitriol is also being explored in research for its potential roles in immune modulation and cancer therapy. Its effectiveness in promoting cellular differentiation and inhibiting proliferation can be leveraged in developing novel treatment strategies. With its multifaceted applications in both healthcare and research, Calcitriol stands out as a vital compound for professionals seeking to enhance patient outcomes or explore new therapeutic avenues.

Synonyms
1a,25-Dihydroxyvitamin D3, 1,25-Dihydroxycholecalciferol
CAS Number
32222-06-3
Purity
≥ 97% (HPLC)
Molecular Formula
C27H44O3
Molecular Weight
416.65
MDL Number
MFCD00867079
PubChem ID
2524
Melting Point
119 ?C
Appearance
White to almost white powder to crystal
Conditions
Store at < 0 °C
General Information
Synonyms
1a,25-Dihydroxyvitamin D3, 1,25-Dihydroxycholecalciferol
CAS Number
32222-06-3
Purity
≥ 97% (HPLC)
Molecular Formula
C27H44O3
Molecular Weight
416.65
MDL Number
MFCD00867079
PubChem ID
2524
Melting Point
119 ?C
Appearance
White to almost white powder to crystal
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Calcitriol is widely utilized in research focused on:

  • Bone Health: It plays a crucial role in calcium metabolism and is used in treatments for osteoporosis and other bone-related disorders, helping to strengthen bones and reduce fracture risk.
  • Kidney Disease Management: Calcitriol is essential for patients with chronic kidney disease, as it helps manage calcium and phosphate levels, preventing complications like bone disease.
  • Autoimmune Disorders: Research indicates that calcitriol may have immunomodulatory effects, making it a candidate for therapies aimed at autoimmune diseases such as multiple sclerosis.
  • Cancer Research: Studies are exploring its potential role in cancer therapy, particularly in enhancing the efficacy of certain treatments and reducing tumor growth in specific types of cancer.
  • Dermatology: Calcitriol is used in topical formulations for skin conditions like psoriasis, offering a way to reduce scaling and inflammation effectively.

Citations