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Catalog Number:
37724
CAS Number:
73963-72-1
Cilostazol
Purity:
≥ 99% (Assay)
Synonym(s):
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
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Product Information

Cilostazol is a potent phosphodiesterase III inhibitor, primarily utilized in the management of intermittent claudication, a condition characterized by muscle pain due to inadequate blood flow. This compound enhances blood flow by inhibiting platelet aggregation and promoting vasodilation, making it a valuable therapeutic agent in cardiovascular health. Cilostazol's unique mechanism of action not only alleviates symptoms associated with claudication but also improves walking distance and overall quality of life for patients.

In addition to its primary use in treating peripheral vascular disease, Cilostazol is being explored for its potential benefits in other areas, such as stroke prevention and improving outcomes in patients with coronary artery disease. Its favorable safety profile and effectiveness make it a preferred choice among healthcare professionals. Researchers and industry professionals can leverage Cilostazol's properties for innovative applications in drug development and clinical research, contributing to advancements in cardiovascular therapies.

Synonyms
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS Number
73963-72-1
Purity
≥ 99% (Assay)
Molecular Formula
C20H27N5O2
Molecular Weight
369.47
MDL Number
MFCD00866780
PubChem ID
2754
Melting Point
158 - 162 °C
Appearance
White crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS Number
73963-72-1
Purity
≥ 99% (Assay)
Molecular Formula
C20H27N5O2
Molecular Weight
369.47
MDL Number
MFCD00866780
PubChem ID
2754
Melting Point
158 - 162 °C
Appearance
White crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Cilostazol is widely utilized in research focused on:

  • Cardiovascular Health: Primarily used to treat intermittent claudication, cilostazol improves blood flow and reduces pain during physical activity, making it essential for patients with peripheral artery disease.
  • Anti-platelet Activity: Its ability to inhibit platelet aggregation makes cilostazol valuable in preventing thrombotic events, particularly in patients at risk for stroke or heart attack.
  • Research on Metabolic Disorders: Studies indicate cilostazol may have beneficial effects on insulin sensitivity and lipid profiles, making it a candidate for research in diabetes and metabolic syndrome.
  • Neuroprotective Effects: Emerging research suggests cilostazol may offer neuroprotective benefits, potentially aiding in the treatment of neurodegenerative diseases such as Alzheimer’s.
  • Combination Therapies: Cilostazol is often explored in combination with other medications to enhance therapeutic outcomes, particularly in cardiovascular and metabolic health, providing a synergistic effect that can improve patient care.

Citations