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Catalog Number:
37703
CAS Number:
62571-86-2
Captopril
Purity:
≥ 98% (HPLC)
Synonym(s):
(S)-(-)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline, (S)-(-)-1-(3-Mercapto-2-methylpropionyl)-L-proline
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Product Information

Captopril is a potent angiotensin-converting enzyme (ACE) inhibitor widely utilized in the management of hypertension and heart failure. This compound is particularly valued for its ability to lower blood pressure and improve heart function by inhibiting the conversion of angiotensin I to angiotensin II, a substance that narrows blood vessels. Captopril is also employed in the treatment of diabetic nephropathy, showcasing its versatility in addressing various cardiovascular and renal conditions. Its unique structure allows for effective oral bioavailability, making it a preferred choice in clinical settings.

In addition to its therapeutic applications, Captopril is a valuable tool in research, particularly in studies related to cardiovascular health and drug development. Its role in understanding the mechanisms of hypertension and heart disease has made it a staple in pharmacological research. The compound's established safety profile and efficacy further enhance its appeal to healthcare professionals and researchers alike, making it an essential addition to any pharmaceutical or research-focused portfolio.

Synonyms
(S)-(-)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline, (S)-(-)-1-(3-Mercapto-2-methylpropionyl)-L-proline
CAS Number
62571-86-2
Purity
≥ 98% (HPLC)
Molecular Formula
C9H15NO3S
Molecular Weight
217.28
MDL Number
MFCD00168073
PubChem ID
2550
Melting Point
105 - 110 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -125 to -134 ° (C=1 in EtOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(S)-(-)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline, (S)-(-)-1-(3-Mercapto-2-methylpropionyl)-L-proline
CAS Number
62571-86-2
Purity
≥ 98% (HPLC)
Molecular Formula
C9H15NO3S
Molecular Weight
217.28
MDL Number
MFCD00168073
PubChem ID
2550
Melting Point
105 - 110 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -125 to -134 ° (C=1 in EtOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Captopril is widely utilized in research focused on

  • Hypertension Treatment: As an effective ACE inhibitor, it helps lower blood pressure, making it a cornerstone in managing hypertension.
  • Heart Failure Management: Captopril is used to improve survival rates in patients with heart failure by reducing the workload on the heart.
  • Diabetic Nephropathy: It protects kidney function in diabetic patients, reducing the risk of kidney damage.
  • Research on Cardiovascular Diseases: Captopril is often used in clinical studies to explore new treatments for various cardiovascular conditions.
  • Pharmaceutical Development: Its unique properties make it a model compound for developing new antihypertensive drugs, providing insights into drug design.

Citations