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Catalog Number:
37641
CAS Number:
378-44-9
Betamethasone
Grade:
Meets USP specification
Purity:
97 - 103% (Assay on dried basis)
Synonym(s):
9a-Fluoro-11ß,17a,21-trihydroxy-16ß-methyl-1,4-pregnadiene-3,20-dione, 9a-Fluoro-16b-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione
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Product Information

Betamethasone is a potent synthetic corticosteroid known for its anti-inflammatory and immunosuppressive properties. This compound is widely utilized in the medical field for the treatment of various conditions, including allergies, skin disorders, and autoimmune diseases. Its effectiveness in reducing inflammation makes it a preferred choice for managing chronic conditions such as arthritis and asthma. Additionally, Betamethasone is often employed in dermatological preparations to alleviate symptoms associated with eczema and psoriasis, providing rapid relief and improved skin health.

In research and pharmaceutical applications, Betamethasone's unique properties enable it to be formulated in various dosage forms, including creams, ointments, and injectable solutions. Its versatility allows for targeted therapy, ensuring that patients receive optimal treatment tailored to their specific needs. The compound's ability to modulate immune responses also opens avenues for its use in transplant medicine and cancer therapy, where controlling inflammation is crucial. With its established efficacy and broad range of applications, Betamethasone remains a vital compound in both clinical and research settings.

Synonyms
9a-Fluoro-11ß,17a,21-trihydroxy-16ß-methyl-1,4-pregnadiene-3,20-dione, 9a-Fluoro-16b-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione
CAS Number
378-44-9
Purity
97 - 103% (Assay on dried basis)
Grade
Meets USP specification
Molecular Formula
C22H29FO5
Molecular Weight
392.47
MDL Number
MFCD00062969
PubChem ID
3003
Melting Point
235 - 237 °C
Appearance
A white or almost white crystalline powde
Optical Rotation
[a]D20 : 118 - 126 ° (C=5 in methanol)
Conditions
Store at RT
General Information
Synonyms
9a-Fluoro-11ß,17a,21-trihydroxy-16ß-methyl-1,4-pregnadiene-3,20-dione, 9a-Fluoro-16b-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione
CAS Number
378-44-9
Purity
97 - 103% (Assay on dried basis)
Grade
Meets USP specification
Molecular Formula
C22H29FO5
Molecular Weight
392.47
MDL Number
MFCD00062969
PubChem ID
3003
Melting Point
235 - 237 °C
Appearance
A white or almost white crystalline powde
Optical Rotation
[a]D20 : 118 - 126 ° (C=5 in methanol)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Betamethasone is widely utilized in research focused on:

  • Anti-inflammatory Treatments: Commonly used in pharmaceuticals to reduce inflammation in conditions such as arthritis and skin disorders, providing relief and improving quality of life for patients.
  • Dermatology: Applied in topical formulations for treating skin conditions like eczema and psoriasis, offering effective symptom management and promoting skin healing.
  • Allergy Management: Utilized in allergy medications to alleviate symptoms from severe allergic reactions, helping individuals manage their conditions effectively.
  • Respiratory Conditions: Administered in inhalers for asthma and chronic obstructive pulmonary disease (COPD), aiding in the reduction of airway inflammation and improving breathing.
  • Veterinary Medicine: Employed in animal healthcare for treating inflammatory conditions in pets and livestock, ensuring better health outcomes in veterinary practices.

Citations