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Catalog Number:
37573
CAS Number:
111470-99-6
Amlodipine besylate
Purity:
≥ 98% (HPLC)
Synonym(s):
3-Ethyl 5-methyl2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylateBenzenesulfonate, 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylicacid 3-ethyl 5-methyl ester benzenesulfonate
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Product Information

Amlodipine besylate is a widely utilized pharmaceutical compound known for its effectiveness as a calcium channel blocker, primarily used in the treatment of hypertension and angina. This compound operates by relaxing blood vessels, thereby improving blood flow and reducing the heart's workload. Its unique formulation allows for a prolonged therapeutic effect, making it a preferred choice in managing chronic conditions. Amlodipine besylate is often prescribed in combination with other antihypertensive agents, enhancing its efficacy and providing a comprehensive approach to cardiovascular health.

In addition to its primary applications in cardiovascular therapy, Amlodipine besylate has shown potential in various research settings, including studies focused on its effects on renal function and its role in preventing complications associated with diabetes. Its favorable safety profile and versatility make it an essential compound for both clinical and research applications, providing significant benefits to patients and healthcare providers alike.

Synonyms
3-Ethyl 5-methyl2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylateBenzenesulfonate, 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylicacid 3-ethyl 5-methyl ester benzenesulfonate
CAS Number
111470-99-6
Purity
≥ 98% (HPLC)
Molecular Formula
C20H25ClN2O5·C6H5SO3H
Molecular Weight
567.05
MDL Number
MFCD00887594
PubChem ID
60496
Melting Point
200 °C (dec.)
Appearance
White to dark green powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
3-Ethyl 5-methyl2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylateBenzenesulfonate, 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylicacid 3-ethyl 5-methyl ester benzenesulfonate
CAS Number
111470-99-6
Purity
≥ 98% (HPLC)
Molecular Formula
C20H25ClN2O5·C6H5SO3H
Molecular Weight
567.05
MDL Number
MFCD00887594
PubChem ID
60496
Melting Point
200 °C (dec.)
Appearance
White to dark green powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Amlodipine besylate is widely utilized in research focused on:

  • Hypertension Treatment: This compound is primarily used in the pharmaceutical industry to manage high blood pressure, helping to reduce the risk of heart disease and stroke.
  • Angina Management: It is effective in treating angina pectoris, providing relief from chest pain associated with heart conditions, thus improving patients' quality of life.
  • Cardiovascular Research: Researchers use amlodipine besylate to study its effects on vascular smooth muscle cells, contributing to the development of new cardiovascular therapies.
  • Combination Therapies: It is often combined with other antihypertensive agents, enhancing treatment efficacy and allowing for lower doses of each medication, which can minimize side effects.
  • Patient Compliance: The formulation of amlodipine besylate allows for once-daily dosing, which improves adherence to medication regimens among patients.

Citations