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Catalog Number:
37569
CAS Number:
71963-77-4
Artemether
Purity:
≥ 98% (HPLC)
Synonym(s):
Dihydroartemisinin methyl ether, Dihydroqinghaosu methyl ether
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Product Information

Artemether is a potent antimalarial compound derived from artemisinin, known for its effectiveness in treating malaria, particularly in cases of drug-resistant strains. This semi-synthetic derivative offers enhanced bioavailability and a rapid onset of action, making it a preferred choice in combination therapies for malaria treatment. Its unique structure allows for a dual mechanism of action, targeting both the parasite and the host's immune response, which significantly contributes to its therapeutic efficacy.

In addition to its primary use in malaria treatment, Artemether has shown potential in research settings for its anti-inflammatory and immunomodulatory properties. This versatility opens doors for further exploration in various therapeutic areas, including potential applications in treating other parasitic infections. Researchers and healthcare professionals value Artemether for its reliability and effectiveness, making it a critical component in the fight against malaria and a promising candidate for future pharmaceutical developments.

Synonyms
Dihydroartemisinin methyl ether, Dihydroqinghaosu methyl ether
CAS Number
71963-77-4
Purity
≥ 98% (HPLC)
Molecular Formula
C16H26O5
Molecular Weight
298.38
MDL Number
MFCD00866205
PubChem ID
500199
Melting Point
86 - 90 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = 166 - 173 ° (C=1 in EtOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Dihydroartemisinin methyl ether, Dihydroqinghaosu methyl ether
CAS Number
71963-77-4
Purity
≥ 98% (HPLC)
Molecular Formula
C16H26O5
Molecular Weight
298.38
MDL Number
MFCD00866205
PubChem ID
500199
Melting Point
86 - 90 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = 166 - 173 ° (C=1 in EtOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Artemether is widely utilized in research focused on:

  • Treatment of Malaria: Primarily used as an antimalarial drug, it effectively treats uncomplicated malaria caused by Plasmodium falciparum, offering rapid relief and reducing the risk of severe disease.
  • Combination Therapies: Often combined with lumefantrine in co-formulated treatments, enhancing efficacy and reducing the likelihood of resistance development, making it a preferred choice in malaria-endemic regions.
  • Research in Pharmacology: Utilized in studies examining drug interactions and pharmacokinetics, helping researchers understand its behavior in the body and optimize dosing regimens for better patient outcomes.
  • Veterinary Medicine: Employed in treating malaria in animals, particularly in regions where zoonotic transmission is a concern, thus protecting livestock and supporting agricultural productivity.
  • Development of New Antimalarials: Serves as a lead compound in the synthesis of novel antimalarial agents, inspiring research into derivatives that may offer improved efficacy or reduced side effects.

Citations