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Catalog Number:
37565
CAS Number:
446-86-6
Azathioprine
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
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$181.67 /5G
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Product Information

Azathioprine is a potent immunosuppressive agent widely utilized in the treatment of autoimmune diseases and organ transplantation. This compound functions by inhibiting the proliferation of lymphocytes, making it invaluable in managing conditions such as rheumatoid arthritis, lupus, and inflammatory bowel disease. Its unique mechanism of action allows for the modulation of the immune response, thereby reducing the risk of organ rejection in transplant patients.

In addition to its therapeutic applications, Azathioprine is also employed in research settings to study immune system functions and the effects of immunosuppression. Its ability to selectively target rapidly dividing cells makes it a critical tool in both clinical and laboratory environments. Researchers appreciate its versatility and effectiveness, particularly in combination therapies, where it can enhance the efficacy of other immunosuppressive agents. With a well-established safety profile and a history of successful application, Azathioprine remains a cornerstone in the management of various immune-mediated conditions.

Synonyms
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
CAS Number
446-86-6
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C9H7N7O2S
Molecular Weight
277.26
MDL Number
MFCD00069203
PubChem ID
2265
Melting Point
244 °C (dec.)
Appearance
Light yellow to yellow to green powder to crystal
Conditions
Store at < 0 °C
General Information
Synonyms
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
CAS Number
446-86-6
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C9H7N7O2S
Molecular Weight
277.26
MDL Number
MFCD00069203
PubChem ID
2265
Melting Point
244 °C (dec.)
Appearance
Light yellow to yellow to green powder to crystal
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Azathioprine is widely utilized in research focused on

  • Autoimmune Disorders: It is commonly prescribed to manage conditions like rheumatoid arthritis and lupus, helping to suppress the immune system and reduce inflammation.
  • Organ Transplantation: Azathioprine plays a crucial role in preventing organ rejection by inhibiting the immune response, making it essential for transplant patients.
  • Cancer Treatment: In oncology, it is used as a chemotherapeutic agent for certain types of leukemia and other malignancies, providing an alternative to more aggressive treatments.
  • Research in Immunology: Scientists utilize azathioprine to study immune system functions and develop new therapies, contributing to advancements in immunotherapy.
  • Cost-Effectiveness: Compared to newer immunosuppressants, azathioprine offers a more affordable option for long-term treatment, making it accessible for many patients.

Citations