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Catalog Number:
37546
CAS Number:
53531-34-3
R-(-)-2,2,2-Trifluoro-1-(9-anthryl)ethanol [e.e. Determination Reagent by NMR]
Purity:
≥ 99% (GC)
Synonym(s):
(R-(-)-1-(9-Anthryl)-2,2,2-trifluoroethanol, (R)-(-)-α-(Trifluoromethyl)anthracene-9-methanol
Documents
$129.19 /100MG
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Product Information

(R)-(-)-2,2,2-Trifluoro-1-(9-anthryl)ethanol is a specialized reagent widely utilized in the field of NMR spectroscopy for enantiomeric excess determination. This compound, also known as (1R)-1-anthracen-9-yl-2,2,2-trifluoroethanol, features a unique trifluoroethanol moiety that enhances its solubility and reactivity, making it an ideal choice for researchers focused on chiral analysis. Its distinctive structure allows for precise differentiation between enantiomers, which is crucial in pharmaceutical development and quality control processes.

In addition to its application in NMR, this reagent is valuable in organic synthesis, particularly in the preparation of chiral intermediates and active pharmaceutical ingredients (APIs). The trifluoromethyl group not only contributes to the compound's stability but also improves its interaction with various substrates, leading to higher yields and more efficient reactions. Researchers and industry professionals can leverage this compound to streamline their workflows and enhance the accuracy of their analytical methods.

Synonyms
(R-(-)-1-(9-Anthryl)-2,2,2-trifluoroethanol, (R)-(-)-α-(Trifluoromethyl)anthracene-9-methanol
CAS Number
53531-34-3
Purity
≥ 99% (GC)
Molecular Formula
C16H11F3O
Molecular Weight
276.26
MDL Number
MFCD00001260
PubChem ID
103802
Melting Point
134 - 136 °C
Appearance
White to Light yellow to Green powder to
Optical Rotation
-30.5 ± 1 ° (C=1,CHCl3)
Conditions
Store at RT
General Information
Synonyms
(R-(-)-1-(9-Anthryl)-2,2,2-trifluoroethanol, (R)-(-)-α-(Trifluoromethyl)anthracene-9-methanol
CAS Number
53531-34-3
Purity
≥ 99% (GC)
Molecular Formula
C16H11F3O
Molecular Weight
276.26
MDL Number
MFCD00001260
PubChem ID
103802
Melting Point
134 - 136 °C
Appearance
White to Light yellow to Green powder to
Optical Rotation
-30.5 ± 1 ° (C=1,CHCl3)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(-)-2,2,2-Trifluoro-1-(9-anthryl)ethanol is widely utilized in research focused on:

  • Chiral Resolution: This compound serves as a reagent in NMR spectroscopy for the determination of enantiomeric excess, aiding chemists in the analysis of chiral compounds.
  • Drug Development: It plays a crucial role in pharmaceutical research, particularly in the development of new drugs that require precise stereochemical configurations.
  • Material Science: The compound is used in the synthesis of novel materials with specific optical properties, beneficial for applications in organic electronics and photonics.
  • Environmental Chemistry: It assists in studying the behavior of pollutants and their interactions in various environments, contributing to environmental monitoring efforts.
  • Analytical Chemistry: This reagent enhances the accuracy of analytical methods, providing reliable data for researchers working with complex mixtures.

Citations