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Catalog Number:
37537
CAS Number:
17257-71-5
(S-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid [Optical Resolving]
Purity:
≥ 98% (GC)(T)
Synonym(s):
(-)-Mosher's acid, (-)-MTPA
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Product Information

(S)-(-)-a-Methoxy-a-(trifluoromethyl)phenylacetic acid is a valuable compound known for its unique trifluoromethyl and methoxy functional groups, which enhance its reactivity and selectivity in various chemical reactions. This compound is particularly significant in the pharmaceutical industry, where it serves as a key intermediate in the synthesis of chiral drugs. Its optical resolving capabilities make it an essential tool for researchers aiming to produce enantiomerically pure compounds, which are critical for developing effective medications with minimal side effects.

In addition to its applications in drug synthesis, (S)-(-)-a-Methoxy-a-(trifluoromethyl)phenylacetic acid is also utilized in agrochemical formulations and materials science, where its unique properties can improve the performance and efficacy of various products. Researchers and industry professionals appreciate its versatility and effectiveness, making it a sought-after compound for innovative applications in multiple fields.

Synonyms
(-)-Mosher's acid, (-)-MTPA
CAS Number
17257-71-5
Purity
≥ 98% (GC)(T)
Molecular Formula
C10H9F3O3
Molecular Weight
234.17
MDL Number
MFCD00064200
PubChem ID
86531
Melting Point
34 °C
Appearance
White to Almost white powder to lump
Optical Rotation
[α]20D = -70 to -75 ° (C=2, Methanol)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(-)-Mosher's acid, (-)-MTPA
CAS Number
17257-71-5
Purity
≥ 98% (GC)(T)
Molecular Formula
C10H9F3O3
Molecular Weight
234.17
MDL Number
MFCD00064200
PubChem ID
86531
Melting Point
34 °C
Appearance
White to Almost white powder to lump
Optical Rotation
[α]20D = -70 to -75 ° (C=2, Methanol)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(-)-a-Methoxy-a-(trifluoromethyl)phenylacetic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs that target specific receptors, enhancing therapeutic efficacy.
  • Chiral Resolution: Its optical resolving properties make it valuable in separating enantiomers, which is crucial in the production of chiral drugs, ensuring higher purity and effectiveness.
  • Material Science: It is used in the formulation of advanced materials, including polymers and coatings, where its unique chemical structure contributes to improved performance characteristics.
  • Agricultural Chemistry: The compound finds applications in the synthesis of agrochemicals, aiding in the development of more effective pesticides and herbicides that are safer for the environment.
  • Research and Development: In academic and industrial laboratories, it is employed in various research projects aimed at exploring new chemical reactions and developing innovative applications in organic synthesis.

Citations