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Catalog Number:
37502
CAS Number:
1446-61-3
+)-Dehydroabietylamine [Optical Resolving Agent]
Purity:
≥ 90% (GC)
Synonym(s):
1,4a-Dimethyl-7-isopropyl-1,2,3,4,4a,9,10,10a-octahydro-1-phenanthrenemethylamine
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Product Information

(+)-Dehydroabietylamine is a versatile optical resolving agent widely utilized in the synthesis of chiral compounds. This compound is particularly valuable in the pharmaceutical industry, where it aids in the resolution of racemic mixtures, allowing for the isolation of enantiomers that exhibit distinct biological activities. Its unique structure, derived from natural sources, enhances its effectiveness in various applications, including asymmetric synthesis and the production of fine chemicals. Researchers and industry professionals appreciate its ability to improve yields and selectivity in chemical reactions, making it an essential tool in drug development and other chemical processes.

In addition to its role in pharmaceuticals, (+)-Dehydroabietylamine is also employed in the production of agrochemicals and specialty chemicals, where its chiral properties contribute to the development of more effective and environmentally friendly products. Its compatibility with various reaction conditions and its ability to facilitate complex transformations make it a preferred choice among chemists. As a result, this compound not only streamlines the synthesis process but also enhances the overall quality of the end products, providing significant advantages over traditional resolving agents.

Synonyms
1,4a-Dimethyl-7-isopropyl-1,2,3,4,4a,9,10,10a-octahydro-1-phenanthrenemethylamine
CAS Number
1446-61-3
Purity
≥ 90% (GC)
Molecular Formula
C20H31N
Molecular Weight
285.48
MDL Number
MFCD00213430
PubChem ID
106831
Melting Point
38 - 42 °C
Appearance
White to Orange to Green powder to lump
Optical Rotation
[α]20D = 40 - 50 ° (C=4,MeOH)
Conditions
Store at RT
General Information
Synonyms
1,4a-Dimethyl-7-isopropyl-1,2,3,4,4a,9,10,10a-octahydro-1-phenanthrenemethylamine
CAS Number
1446-61-3
Purity
≥ 90% (GC)
Molecular Formula
C20H31N
Molecular Weight
285.48
MDL Number
MFCD00213430
PubChem ID
106831
Melting Point
38 - 42 °C
Appearance
White to Orange to Green powder to lump
Optical Rotation
[α]20D = 40 - 50 ° (C=4,MeOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(+)-Dehydroabietylamine is widely utilized in research focused on:

  • Optical Resolution: This compound serves as an effective resolving agent for chiral compounds, aiding in the separation of enantiomers, which is crucial in pharmaceuticals where the efficacy and safety of drugs can vary significantly between different stereoisomers.
  • Pharmaceutical Synthesis: It plays a vital role in the synthesis of various pharmaceutical intermediates, enhancing the production of active pharmaceutical ingredients (APIs) that require specific chiral configurations for optimal therapeutic effects.
  • Polymer Chemistry: The compound is used in the development of chiral polymers, which can improve the performance of materials in applications such as drug delivery systems and sensors, offering tailored properties for specific uses.
  • Biochemical Research: Researchers utilize it to study enzyme interactions and metabolic pathways, providing insights into biological processes that are essential for drug development and disease treatment.
  • Environmental Applications: It is also explored in the field of environmental chemistry for the remediation of pollutants, particularly in processes that require selective binding to specific contaminants, thus enhancing the efficiency of cleanup efforts.

Citations