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Catalog Number:
37454
CAS Number:
1185-53-1
2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride
Grade:
Molecular Biology Grade
Purity:
≥ 99% (Assay)
Synonym(s):
Tris(hydroxymethyl)aminomethane hydrochloride, TRIS hydrochloride
Documents
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Product Information

2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride, commonly known as Tromethamine hydrochloride, is a versatile compound widely utilized in pharmaceutical formulations and biochemical applications. This compound serves as an effective buffering agent, maintaining pH stability in various biological and chemical systems, which is crucial for the efficacy of many drugs and biological assays. Its ability to stabilize pH makes it particularly valuable in the preparation of injectable solutions and intravenous medications, ensuring patient safety and drug effectiveness.

Additionally, Tromethamine hydrochloride is employed in cell culture media, where it supports optimal growth conditions for various cell types, enhancing research outcomes in biotechnology and pharmaceutical development. Its unique properties allow for precise control over pH levels, making it an essential component in laboratory settings. Researchers and industry professionals appreciate its compatibility with a wide range of formulations, making it an indispensable tool in drug development and biochemical research.

Synonyms
Tris(hydroxymethyl)aminomethane hydrochloride, TRIS hydrochloride
CAS Number
1185-53-1
Purity
≥ 99% (Assay)
Grade
Molecular Biology Grade
Molecular Formula
C4H11NO3·HCl
Molecular Weight
157.6
MDL Number
MFCD00012590
PubChem ID
93573
Melting Point
150 - 153 °C
Appearance
White crystalline powder
Conditions
Store at RT
General Information
Synonyms
Tris(hydroxymethyl)aminomethane hydrochloride, TRIS hydrochloride
CAS Number
1185-53-1
Purity
≥ 99% (Assay)
Grade
Molecular Biology Grade
Molecular Formula
C4H11NO3·HCl
Molecular Weight
157.6
MDL Number
MFCD00012590
PubChem ID
93573
Melting Point
150 - 153 °C
Appearance
White crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride is widely utilized in research focused on:

  • Pharmaceutical Formulations: This compound serves as a stabilizer in various drug formulations, enhancing the solubility and bioavailability of active pharmaceutical ingredients.
  • Biotechnology: It is used as a buffering agent in cell culture media, providing an optimal pH environment for the growth of cells and microorganisms, which is crucial for biopharmaceutical production.
  • Cosmetic Products: The compound acts as a humectant in skincare formulations, helping to retain moisture and improve skin hydration, making it a popular choice in moisturizers and serums.
  • Research Reagents: It is employed in biochemical assays and laboratory experiments, particularly in studies involving enzyme activity and protein stability, due to its ability to maintain pH levels.
  • Food Industry: Used as a food additive, it helps in maintaining the texture and stability of various food products, ensuring quality and safety for consumers.

Citations