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Catalog Number:
37441
CAS Number:
98541-64-1
Boc-L-serine-β-lactone
Purity:
≥ 98% (HPLC)
Synonym(s):
(S)-α-Boc-amino-b-propiolactone, (S)-3-(tert-Butoxycarbonylamino)-2-oxetanone
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Product Information

Boc-L-serine-b-lactone is a versatile chemical compound widely utilized in the synthesis of peptides and other bioactive molecules. This compound features a unique b-lactone structure that enhances its reactivity, making it an excellent choice for researchers focused on developing novel therapeutics and biomaterials. Its ability to selectively react with amines allows for the efficient incorporation of L-serine into peptide chains, facilitating the creation of complex structures that are crucial in drug discovery and development. Additionally, Boc-L-serine-b-lactone serves as a valuable intermediate in the production of various pharmaceuticals, particularly in the fields of medicinal chemistry and biochemistry.

The compound's stability and ease of handling make it suitable for both academic and industrial applications. Researchers appreciate its role in the synthesis of modified amino acids and its potential in creating peptide-based drugs with enhanced biological activity. With its favorable properties and practical applications, Boc-L-serine-b-lactone stands out as a key reagent for professionals aiming to innovate in the fields of drug development and peptide synthesis.

Synonyms
(S)-α-Boc-amino-b-propiolactone, (S)-3-(tert-Butoxycarbonylamino)-2-oxetanone
CAS Number
98541-64-1
Purity
≥ 98% (HPLC)
Molecular Formula
C8H13NO4
Molecular Weight
187.2
MDL Number
MFCD01318414
PubChem ID
11789941
Melting Point
120 - 124 ?C
Appearance
White or off-white powder
Boiling Point
318 - 320 ?C
Optical Rotation
[a]D20 = -26 ± 2 ° (C=1 in ACN)
Conditions
Store at -10 °C
General Information
Synonyms
(S)-α-Boc-amino-b-propiolactone, (S)-3-(tert-Butoxycarbonylamino)-2-oxetanone
CAS Number
98541-64-1
Purity
≥ 98% (HPLC)
Molecular Formula
C8H13NO4
Molecular Weight
187.2
MDL Number
MFCD01318414
PubChem ID
11789941
Melting Point
120 - 124 ?C
Appearance
White or off-white powder
Boiling Point
318 - 320 ?C
Optical Rotation
[a]D20 = -26 ± 2 ° (C=1 in ACN)
Conditions
Store at -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-serine-b-lactone is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in creating modified amino acids that enhance the stability and bioactivity of therapeutic peptides.
  • Drug Development: Its unique structure allows for the design of novel pharmaceuticals, especially in the development of inhibitors or modulators targeting specific biological pathways.
  • Bioconjugation: Researchers use it for bioconjugation processes to attach biomolecules to surfaces or other molecules, improving the efficacy of drug delivery systems.
  • Material Science: The compound is explored in creating advanced materials, such as hydrogels, which can be used in tissue engineering and regenerative medicine.
  • Analytical Chemistry: It is employed in analytical methods for detecting and quantifying amino acids and related compounds, providing essential data for various biochemical studies.

Citations