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Catalog Number:
36624
CAS Number:
40949-94-8
Potassium bis(trimethylsilyl)amide
Purity:
≥ 96% (Assay)
Synonym(s):
Hexamethyldisilazane potassium salt, Potassium hexamethyldisilazide
Hazmat
Documents
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Product Information

Potassium bis(trimethylsilyl)amide is a versatile and highly reactive compound widely utilized in organic synthesis and materials science. This chemical serves as a powerful nucleophile and is particularly effective in deprotonating various substrates, making it an essential reagent in the synthesis of complex organic molecules. Its unique structure allows for enhanced stability and solubility in non-polar solvents, which is advantageous for reactions requiring anhydrous conditions. Researchers and industry professionals often leverage its properties in the development of pharmaceuticals, agrochemicals, and advanced materials, where precision and efficiency are paramount.

In addition to its role in organic synthesis, Potassium bis(trimethylsilyl)amide is also employed in the production of silicon-based polymers and as a catalyst in various chemical reactions. Its ability to facilitate the formation of carbon-nitrogen bonds makes it invaluable in the synthesis of heterocycles and other nitrogen-containing compounds. The compound’s high reactivity and selectivity provide significant advantages over similar reagents, allowing for cleaner reactions and higher yields. Whether in academic research or industrial applications, Potassium bis(trimethylsilyl)amide stands out as a key player in modern chemistry.

Synonyms
Hexamethyldisilazane potassium salt, Potassium hexamethyldisilazide
CAS Number
40949-94-8
Purity
≥ 96% (Assay)
Molecular Formula
C6H18KNSi2
Molecular Weight
199.48
MDL Number
MFCD00010330
PubChem ID
3251421
Density
0.881 (Lit.)
Appearance
White to cream to tan powder
Conditions
Store at RT, under inert gas
General Information
Synonyms
Hexamethyldisilazane potassium salt, Potassium hexamethyldisilazide
CAS Number
40949-94-8
Purity
≥ 96% (Assay)
Molecular Formula
C6H18KNSi2
Molecular Weight
199.48
MDL Number
MFCD00010330
PubChem ID
3251421
Density
0.881 (Lit.)
Appearance
White to cream to tan powder
Conditions
Store at RT, under inert gas
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Potassium bis(trimethylsilyl)amide is widely utilized in research focused on:

  • Synthetic Chemistry: This compound serves as a powerful reagent for deprotonation reactions, enabling the synthesis of various organic compounds, particularly in the creation of complex molecules.
  • Organometallic Chemistry: It plays a crucial role in the preparation of organometallic compounds, which are essential in catalysis and materials science, offering enhanced reactivity compared to traditional reagents.
  • Polymer Science: The compound is used in the development of silicon-based polymers, providing unique properties such as thermal stability and flexibility, which are beneficial in industries like automotive and electronics.
  • Pharmaceuticals: In drug development, it aids in the synthesis of nitrogen-containing heterocycles, which are key components in many pharmaceuticals, thus streamlining the drug discovery process.
  • Material Science: Its application in creating advanced materials, such as coatings and adhesives, allows for improved performance characteristics, making it a preferred choice in high-tech industries.

Citations