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Catalog Number:
36345
CAS Number:
106018-85-3
2-(Trimethylsilyl)ethanesulfonyl chloride
Purity:
≥ 95%
Synonym(s):
2-Trimethylsilylethylsulfonyl chloride
Hazmat
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Product Information

2-(Trimethylsilyl)ethanesulfonyl chloride is a versatile reagent widely utilized in organic synthesis and chemical research. This compound serves as an effective sulfonylating agent, allowing for the introduction of sulfonyl groups into various organic molecules. Its unique trimethylsilyl group enhances its reactivity and solubility, making it an ideal choice for researchers looking to modify substrates in a controlled manner. This compound is particularly valuable in the synthesis of sulfonamides and sulfonylureas, which are crucial in pharmaceutical development, agrochemicals, and materials science.

In addition to its applications in synthetic organic chemistry, 2-(Trimethylsilyl)ethanesulfonyl chloride is also employed in the preparation of functionalized silanes and as a protective group in complex molecule synthesis. Its ability to selectively react under mild conditions makes it a preferred choice for chemists aiming to achieve high yields with minimal side reactions. This compound stands out for its efficiency and effectiveness, providing researchers and industry professionals with a reliable tool for advancing their projects.

Synonyms
2-Trimethylsilylethylsulfonyl chloride
CAS Number
106018-85-3
Purity
≥ 95%
Molecular Formula
C5H13ClO2SSi
Molecular Weight
200.76
MDL Number
MFCD09265153
PubChem ID
9837086
Density
1.059
Appearance
Colorless to light brown liquid
Boiling Point
146.8 ?C
Refractive Index
1.444
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Trimethylsilylethylsulfonyl chloride
CAS Number
106018-85-3
Purity
≥ 95%
Molecular Formula
C5H13ClO2SSi
Molecular Weight
200.76
MDL Number
MFCD09265153
PubChem ID
9837086
Density
1.059
Appearance
Colorless to light brown liquid
Boiling Point
146.8 ?C
Refractive Index
1.444
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-(Trimethylsilyl)ethanesulfonyl chloride is widely utilized in research focused on:

  • Synthetic Chemistry: This compound serves as a versatile reagent in organic synthesis, particularly in the preparation of sulfonamide derivatives, which are important in pharmaceuticals.
  • Pharmaceutical Development: It is used in the modification of drug molecules, enhancing their solubility and bioavailability, which is crucial for effective medication formulations.
  • Analytical Chemistry: The compound acts as a derivatizing agent for the analysis of amines and alcohols, improving detection sensitivity in chromatographic techniques.
  • Material Science: It plays a role in the development of functionalized polymers, contributing to advancements in coatings and adhesives with improved performance characteristics.
  • Biotechnology: This chemical is utilized in the preparation of sulfonylated biomolecules, aiding in the study of biological processes and the development of diagnostic tools.

Citations