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Catalog Number:
35987
CAS Number:
3607-17-8
3-Bromopropyl)triphenylphosphonium bromide
Purity:
≥ 98% (Assay)
Documents
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Product Information

(3-Bromopropyl)triphenylphosphonium bromide is a versatile quaternary ammonium compound widely utilized in organic synthesis and medicinal chemistry. This compound serves as a powerful reagent for the introduction of the triphenylphosphonium group into various organic molecules, facilitating the synthesis of phosphonium salts and other derivatives. Its unique structure allows for effective applications in the development of targeted drug delivery systems and in the study of biological processes, particularly in the realm of cell biology and biochemistry. Researchers appreciate its ability to enhance the lipophilicity of compounds, which can improve their cellular uptake and bioavailability.

In addition to its synthetic utility, (3-Bromopropyl)triphenylphosphonium bromide is recognized for its role in the preparation of phosphonium ylides, which are crucial intermediates in the synthesis of alkenes via the Wittig reaction. This compound's stability and reactivity make it an essential tool for chemists looking to explore new pathways in organic synthesis. Its applications extend to the fields of material science and catalysis, where it can be employed in the development of novel materials and catalytic systems.

CAS Number
3607-17-8
Purity
≥ 98% (Assay)
Molecular Formula
C21H21Br2P
Molecular Weight
464.18
MDL Number
MFCD00011866
PubChem ID
2723862
Melting Point
228 - 230??C
Appearance
White to pale yellow powder
Conditions
Store at RT, under inert gas
General Information
CAS Number
3607-17-8
Purity
≥ 98% (Assay)
Molecular Formula
C21H21Br2P
Molecular Weight
464.18
MDL Number
MFCD00011866
PubChem ID
2723862
Melting Point
228 - 230??C
Appearance
White to pale yellow powder
Conditions
Store at RT, under inert gas
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(3-Bromopropyl)triphenylphosphonium bromide is widely utilized in research focused on:

  • Synthesis of Organophosphorus Compounds: This compound serves as a key reagent in the synthesis of various organophosphorus derivatives, which are important in agricultural chemistry for developing pesticides and herbicides.
  • Cellular Biology: It is used in studies involving cellular uptake and transport mechanisms, particularly in the development of phosphonium-based compounds for targeted drug delivery in cancer therapy.
  • Organic Synthesis: The compound acts as a phase-transfer catalyst, facilitating reactions between organic and aqueous phases, which enhances reaction efficiency in organic synthesis.
  • Material Science: It is applied in the development of new materials, particularly in the creation of phosphonium-based ionic liquids that can be used in electrochemical applications.
  • Biological Studies: Researchers utilize it to investigate mitochondrial function, as phosphonium salts can selectively accumulate in mitochondria, aiding in studies related to energy metabolism and apoptosis.

Citations