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Irinotecan hydrochloride anhydrous, Topoisomerase I Inhibitor
Irinotecan hydrochloride anhydrous is widely utilized in research focused on:
- Cancer Treatment: This compound is primarily used in chemotherapy regimens for treating colorectal cancer. It works by inhibiting topoisomerase I, an enzyme crucial for DNA replication, thereby preventing cancer cell proliferation.
- Pharmaceutical Development: Researchers are exploring formulations that enhance the bioavailability and efficacy of irinotecan, making it a focal point in drug development studies aimed at improving cancer therapies.
- Combination Therapies: It is often studied in combination with other anticancer agents to evaluate synergistic effects, helping to develop more effective treatment protocols for various cancers.
- Clinical Trials: Irinotecan is frequently involved in clinical trials assessing its effectiveness and safety in different cancer types, providing valuable data that can influence treatment guidelines.
- Research on Drug Resistance: Scientists are investigating how cancer cells develop resistance to irinotecan, which is critical for developing strategies to overcome this challenge and improve patient outcomes.
General Information
Properties
Safety and Regulations
Applications
Irinotecan hydrochloride anhydrous is widely utilized in research focused on:
- Cancer Treatment: This compound is primarily used in chemotherapy regimens for treating colorectal cancer. It works by inhibiting topoisomerase I, an enzyme crucial for DNA replication, thereby preventing cancer cell proliferation.
- Pharmaceutical Development: Researchers are exploring formulations that enhance the bioavailability and efficacy of irinotecan, making it a focal point in drug development studies aimed at improving cancer therapies.
- Combination Therapies: It is often studied in combination with other anticancer agents to evaluate synergistic effects, helping to develop more effective treatment protocols for various cancers.
- Clinical Trials: Irinotecan is frequently involved in clinical trials assessing its effectiveness and safety in different cancer types, providing valuable data that can influence treatment guidelines.
- Research on Drug Resistance: Scientists are investigating how cancer cells develop resistance to irinotecan, which is critical for developing strategies to overcome this challenge and improve patient outcomes.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
*Catalog Number
*Lot Number
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.