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Catalog Number:
35204
CAS Number:
847658-45-1
Nα-Fmoc-L-lysine methyl ester hydrochloride
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Lys-OMe·HCl
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Product Information

Na-Fmoc-L-lysine methyl ester hydrochloride is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which allows for selective deprotection during the synthesis of peptides, making it an essential building block for researchers in the fields of medicinal chemistry and biotechnology. Its hydrochloride form enhances solubility in various solvents, facilitating easier handling and incorporation into complex reactions.

In addition to its role in peptide synthesis, Na-Fmoc-L-lysine methyl ester hydrochloride is also employed in the development of drug delivery systems and the design of novel biomaterials. Its unique structure allows for the introduction of functional groups that can be tailored for specific applications, such as targeted therapy or diagnostic imaging. Researchers appreciate its stability and compatibility with a range of coupling reagents, making it a preferred choice for high-quality peptide production.

Synonyms
Fmoc-L-Lys-OMe·HCl
CAS Number
847658-45-1
Purity
≥ 99% (HPLC)
Molecular Formula
C22H27ClN2O4
Molecular Weight
418.91
MDL Number
MFCD08275774
PubChem ID
78131017
Melting Point
125 - 127 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -10 ± 1 ° (C=2 in MeOH)
Conditions
Store at -10 °C
General Information
Synonyms
Fmoc-L-Lys-OMe·HCl
CAS Number
847658-45-1
Purity
≥ 99% (HPLC)
Molecular Formula
C22H27ClN2O4
Molecular Weight
418.91
MDL Number
MFCD08275774
PubChem ID
78131017
Melting Point
125 - 127 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -10 ± 1 ° (C=2 in MeOH)
Conditions
Store at -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-L-lysine methyl ester hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides.
  • Drug Development: It is used in the development of pharmaceutical compounds, particularly in creating peptide-based drugs that can target specific biological pathways.
  • Bioconjugation: The chemical is valuable in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing drug delivery systems.
  • Research in Neuroscience: It plays a role in studies related to neurotransmitter signaling, aiding researchers in understanding neurological functions and disorders.
  • Protein Engineering: This compound is utilized in modifying proteins to improve their stability and functionality, which is crucial in biotechnology and therapeutic applications.

Citations