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Catalog Number:
35199
CAS Number:
110797-35-8
Fmoc-L-serine tert-butyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Ser-OtBu
Documents
$154.43 /1G
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Product Information

Fmoc-L-serine tert-butyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential building block for the production of peptides and proteins. Its tert-butyl ester functionality enhances solubility and stability, facilitating smoother reactions and improved yields. Researchers and industry professionals appreciate its role in the development of pharmaceuticals, particularly in the design of peptide-based drugs and therapeutic agents.

In addition to its applications in peptide synthesis, Fmoc-L-serine tert-butyl ester is also valuable in the field of materials science, where it can be used to create functionalized surfaces and biomaterials. Its unique properties allow for the incorporation of serine residues into various polymer matrices, enhancing biocompatibility and functionality. This compound stands out among similar products due to its ease of use and effectiveness in diverse applications, making it a preferred choice for researchers aiming to innovate in drug development and biomaterials.

Synonyms
Fmoc-L-Ser-OtBu
CAS Number
110797-35-8
Purity
≥ 99% (HPLC)
Molecular Formula
C22H25NO5
Molecular Weight
383.44
MDL Number
MFCD01861331
PubChem ID
13965220
Melting Point
122 - 128 °C (Lit.)
Appearance
White solid
Optical Rotation
[a]D20 = -15 ± 2 ° (C=1 in MeOH)
Conditions
Store at RT
General Information
Synonyms
Fmoc-L-Ser-OtBu
CAS Number
110797-35-8
Purity
≥ 99% (HPLC)
Molecular Formula
C22H25NO5
Molecular Weight
383.44
MDL Number
MFCD01861331
PubChem ID
13965220
Melting Point
122 - 128 °C (Lit.)
Appearance
White solid
Optical Rotation
[a]D20 = -15 ± 2 ° (C=1 in MeOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-serine tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for serine residues during peptide synthesis, allowing for the selective modification of amino acids without interference from other functional groups.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, enhancing the stability and bioavailability of therapeutic agents.
  • Bioconjugation: Researchers employ this chemical in bioconjugation processes, linking peptides to various biomolecules for targeted drug delivery systems.
  • Protein Engineering: It aids in the design of modified proteins with improved properties, such as increased solubility or altered activity, which is crucial in biotechnology applications.
  • Analytical Chemistry: The compound is also used in analytical methods to study protein interactions and dynamics, providing insights into biological processes.

Citations