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Catalog Number:
35197
CAS Number:
119894-20-1
Fmoc-O-ethyl-L-tyrosine
Purity:
≥ 99% (Chiral HPLC, HPLC)
Synonym(s):
Fmoc-L-Tyr(Et)-OH, Fmoc-(S-2-amino-3-(4-ethoxyphenyl)propionic acid
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Product Information

Fmoc-O-ethyl-L-tyrosine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its ethoxy substituent enhances solubility and stability, making it an ideal choice for researchers in the fields of medicinal chemistry and biochemistry. Fmoc-O-ethyl-L-tyrosine is particularly valuable in the synthesis of bioactive peptides, which have applications in pharmaceuticals, diagnostics, and therapeutic agents.

Researchers appreciate the compound's ability to facilitate the formation of complex peptide structures while maintaining high purity and yield. Its unique properties allow for efficient coupling reactions, making it a preferred choice for solid-phase peptide synthesis. Additionally, Fmoc-O-ethyl-L-tyrosine's compatibility with various coupling reagents and its ease of deprotection further enhance its utility in laboratory settings. This compound stands out for its role in advancing peptide-based research and development, offering significant advantages over traditional amino acids in terms of reactivity and functionalization.

Synonyms
Fmoc-L-Tyr(Et)-OH, Fmoc-(S-2-amino-3-(4-ethoxyphenyl)propionic acid
CAS Number
119894-20-1
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C26H25NO5
Molecular Weight
431.47
MDL Number
MFCD02094093
PubChem ID
74765196
Melting Point
140 - 144 ?C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -28 ± 1 ° (C=1 in DMF)
Conditions
Store at RT
General Information
Synonyms
Fmoc-L-Tyr(Et)-OH, Fmoc-(S-2-amino-3-(4-ethoxyphenyl)propionic acid
CAS Number
119894-20-1
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C26H25NO5
Molecular Weight
431.47
MDL Number
MFCD02094093
PubChem ID
74765196
Melting Point
140 - 144 ?C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -28 ± 1 ° (C=1 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-ethyl-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), where its protective group facilitates the sequential addition of amino acids.
  • Drug Development: Researchers leverage its unique properties to design and develop new pharmaceuticals, especially those targeting neurological disorders, due to its structural similarity to neurotransmitters.
  • Bioconjugation: Its reactive functional groups allow for efficient conjugation with biomolecules, enhancing the development of targeted drug delivery systems and diagnostic agents.
  • Fluorescent Labeling: The compound can be used in labeling techniques, aiding in the visualization of proteins and cellular components in biological studies, which is crucial for understanding cellular functions.
  • Material Science: In the field of polymers, it is used to create functional materials with specific properties, such as improved biocompatibility for medical devices.

Citations