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Catalog Number:
35193
CAS Number:
51773-92-3
Mefloquine hydrochloride
Purity:
≥ 99% (HPLC)
Synonym(s):
(αS)-rel-α-(2R-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol monohydrochloride
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Product Information

Mefloquine hydrochloride is a potent antimalarial agent primarily used in the prevention and treatment of malaria, particularly in areas where resistance to other antimalarials is prevalent. This compound is recognized for its unique mechanism of action, which disrupts the growth of the malaria parasite within red blood cells. Its efficacy makes it a valuable option for travelers and individuals in endemic regions, providing a reliable defense against malaria. Mefloquine hydrochloride is also being explored for its potential in treating other parasitic infections, showcasing its versatility in pharmaceutical applications.

In addition to its primary use in malaria treatment, Mefloquine hydrochloride has been studied for its neuroprotective properties, indicating potential applications in treating neurological disorders. Its favorable pharmacokinetic profile allows for once-weekly dosing, enhancing patient compliance. Researchers and healthcare professionals appreciate Mefloquine hydrochloride for its effectiveness and the convenience it offers in malaria prophylaxis, making it an essential compound in the fight against this life-threatening disease.

Synonyms
(αS)-rel-α-(2R-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol monohydrochloride
CAS Number
51773-92-3
Purity
≥ 99% (HPLC)
Molecular Formula
C17H17ClF6N2O
Molecular Weight
414.77
MDL Number
MFCD00797519
PubChem ID
441362
Melting Point
259 - 264 ?C
Appearance
Slight yellow to white crystalline powder
Conditions
Store at RT
General Information
Synonyms
(αS)-rel-α-(2R-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol monohydrochloride
CAS Number
51773-92-3
Purity
≥ 99% (HPLC)
Molecular Formula
C17H17ClF6N2O
Molecular Weight
414.77
MDL Number
MFCD00797519
PubChem ID
441362
Melting Point
259 - 264 ?C
Appearance
Slight yellow to white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mefloquine hydrochloride is widely utilized in research focused on

  • Antimalarial Treatment: This compound is primarily used in the treatment and prevention of malaria, particularly in areas where resistance to other antimalarial drugs is prevalent. Its effectiveness in combating Plasmodium falciparum makes it a critical option for healthcare providers.
  • Pharmaceutical Research: Researchers study mefloquine hydrochloride to understand its pharmacokinetics and pharmacodynamics, which helps in the development of new formulations and delivery methods that enhance its efficacy.
  • Veterinary Medicine: The compound is also explored for its potential use in treating malaria in animals, particularly in regions where zoonotic transmission occurs, providing a vital tool for veterinarians.
  • Travel Medicine: Mefloquine hydrochloride is recommended for travelers visiting malaria-endemic regions, offering a preventive measure that is easy to administer and has a favorable dosing schedule.
  • Research on Neuropsychiatric Effects: Ongoing studies investigate the neuropsychiatric side effects associated with mefloquine, contributing to a better understanding of drug safety and informing clinical guidelines for its use.

Citations