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Catalog Number:
35192
CAS Number:
133852-23-0
Fmoc-L-tyrosine tert-butyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Tyr-OtBu
Documents
$19.73 /1G
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Product Information

Fmoc-L-tyrosine tert-butyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of the amino group during the synthesis of peptides. Its tert-butyl ester form enhances solubility and stability, making it an ideal choice for solid-phase peptide synthesis (SPPS). Researchers and industry professionals appreciate its role in the development of bioactive peptides, which are crucial in drug discovery and development.

The unique properties of Fmoc-L-tyrosine tert-butyl ester allow for efficient coupling reactions and facilitate the synthesis of complex peptide structures. Its application extends to the production of peptide-based therapeutics, where precise control over amino acid sequences is vital. Additionally, this compound serves as a valuable building block in the synthesis of various biologically active compounds, including those used in cancer therapy and other therapeutic areas. With its proven efficacy and reliability, Fmoc-L-tyrosine tert-butyl ester is an essential tool for researchers aiming to innovate in peptide chemistry.

Synonyms
Fmoc-L-Tyr-OtBu
CAS Number
133852-23-0
Purity
≥ 99% (HPLC)
Molecular Formula
C28H29NO5
Molecular Weight
459.5
MDL Number
MFCD20264831
PubChem ID
67227153
Melting Point
57 - 71 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -9 ± 2 ° (C=1 in DMF)
Conditions
Store at RT
General Information
Synonyms
Fmoc-L-Tyr-OtBu
CAS Number
133852-23-0
Purity
≥ 99% (HPLC)
Molecular Formula
C28H29NO5
Molecular Weight
459.5
MDL Number
MFCD20264831
PubChem ID
67227153
Melting Point
57 - 71 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -9 ± 2 ° (C=1 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-tyrosine tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: Its role in modifying amino acids makes it valuable in the pharmaceutical industry for developing new drugs, particularly those targeting neurological disorders.
  • Bioconjugation: The chemical is used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is crucial in diagnostics and therapeutic applications.
  • Research in Neuroscience: As a derivative of tyrosine, it aids in studies related to neurotransmitter synthesis, helping researchers understand brain function and related disorders.
  • Fluorescent Labeling: It can be used in fluorescent labeling techniques, enhancing the visualization of proteins in cellular studies, which is essential for understanding cellular processes.

Citations