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Catalog Number:
35190
CAS Number:
145038-52-4
Fmoc-L-aspartic acid α-methyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Asp-OMe
Documents
$34.85 /1G
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Product Information

Fmoc-L-aspartic acid a-methyl ester is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers focused on developing complex peptide sequences. The a-methyl ester group enhances its stability and solubility, facilitating easier handling and manipulation in laboratory settings.

In addition to its role in peptide synthesis, Fmoc-L-aspartic acid a-methyl ester is also valuable in the production of bioactive compounds and pharmaceuticals. Its application extends to the development of therapeutic peptides, where precise control over amino acid sequences is crucial. Researchers in medicinal chemistry and biochemistry can leverage this compound to create innovative drug candidates with improved efficacy and specificity. With its favorable properties and practical applications, Fmoc-L-aspartic acid a-methyl ester stands out as a key reagent for advancing peptide-based research and development.

Synonyms
Fmoc-L-Asp-OMe
CAS Number
145038-52-4
Purity
≥ 98% (HPLC)
Molecular Formula
C20H19NO6
Molecular Weight
369.4
MDL Number
MFCD03701473
PubChem ID
53396250
Melting Point
150 - 165 ?C
Appearance
White powder
Optical Rotation
[a]20D = -29 ± 2 º (C=1 in DMF)
Conditions
Store at RT
General Information
Synonyms
Fmoc-L-Asp-OMe
CAS Number
145038-52-4
Purity
≥ 98% (HPLC)
Molecular Formula
C20H19NO6
Molecular Weight
369.4
MDL Number
MFCD03701473
PubChem ID
53396250
Melting Point
150 - 165 ?C
Appearance
White powder
Optical Rotation
[a]20D = -29 ± 2 º (C=1 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-aspartic acid a-methyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity.
  • Drug Development: It plays a crucial role in the development of pharmaceuticals, especially in designing peptide-based drugs that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The compound is used in bioconjugation techniques to attach peptides to other biomolecules, facilitating the development of targeted drug delivery systems and diagnostic tools.
  • Research in Neuroscience: Its derivatives are explored in neuroscience research for their potential to modulate neurotransmitter systems, aiding in the understanding of neurological disorders.
  • Protein Engineering: Fmoc-L-aspartic acid a-methyl ester is utilized in protein engineering to introduce specific amino acid residues, allowing researchers to study protein structure-function relationships effectively.

Citations