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Catalog Number:
35189
CAS Number:
145038-49-9
Fmoc-L-glutamic acid α-methyl ester
Purity:
≥ 99.5% (HPLC)
Synonym(s):
Fmoc-L-Glu-OMe
Documents
$22.43 /1G
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Product Information

Fmoc-L-glutamic acid a-methyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound, characterized by its protective Fmoc (fluorenylmethyloxycarbonyl) group, enhances the stability and solubility of peptides during synthesis, making it an essential building block for researchers in the fields of biochemistry and medicinal chemistry. Its unique structure allows for selective deprotection, facilitating the formation of complex peptides with high purity and yield.

In addition to its role in peptide synthesis, Fmoc-L-glutamic acid a-methyl ester is also valuable in the development of pharmaceuticals and bioactive compounds. Its application extends to the production of peptide-based therapeutics, where it can contribute to the design of novel drugs targeting various diseases. Researchers appreciate its compatibility with automated synthesizers, streamlining the synthesis process and reducing labor costs. With its proven efficacy and reliability, this compound stands out as a preferred choice for professionals seeking to advance their research and development projects.

Synonyms
Fmoc-L-Glu-OMe
CAS Number
145038-49-9
Purity
≥ 99.5% (HPLC)
Molecular Formula
C21H21NO6
Molecular Weight
383.36
MDL Number
MFCD22200617
PubChem ID
21357339
Melting Point
120 - 140°C
Appearance
White powder
Optical Rotation
[a]20D
Conditions
Store at RT
General Information
Synonyms
Fmoc-L-Glu-OMe
CAS Number
145038-49-9
Purity
≥ 99.5% (HPLC)
Molecular Formula
C21H21NO6
Molecular Weight
383.36
MDL Number
MFCD22200617
PubChem ID
21357339
Melting Point
120 - 140°C
Appearance
White powder
Optical Rotation
[a]20D
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-glutamic acid a-methyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex structures with high purity.
  • Drug Development: It serves as a precursor for developing pharmaceutical compounds, especially in the design of drugs targeting neurological disorders, due to its structural similarity to neurotransmitters.
  • Bioconjugation: The compound is used in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Protein Engineering: It aids in the modification of proteins, enhancing their stability and functionality, which is crucial for applications in biotechnology and therapeutic development.
  • Analytical Chemistry: Fmoc-L-glutamic acid a-methyl ester is employed in various analytical techniques, including chromatography, to separate and identify amino acids and peptides effectively.

Citations