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Catalog Number:
35094
CAS Number:
1682653-80-0
Tetrazine-PEG5-NHS ester
Purity:
≥ 95% (HPLC)
Documents
$180.70 /5MG
Pack Size Availability Price
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Product Information

Tetrazine-PEG5-NHS ester is a versatile compound widely utilized in bioconjugation and drug delivery applications. This unique molecule features a tetrazine moiety, which is known for its rapid and selective reaction with trans-cyclooctene (TCO) derivatives, making it an excellent choice for labeling biomolecules with precision. The PEG5 linker enhances solubility and biocompatibility, facilitating its use in various biological environments. Researchers can leverage this compound for the development of targeted therapeutics, imaging agents, and in the creation of complex biomolecular assemblies.

In addition to its robust reactivity, Tetrazine-PEG5-NHS ester offers significant advantages over traditional coupling agents, such as improved stability and reduced background noise in assays. Its application extends to the fields of proteomics, diagnostics, and therapeutic development, where it can be used to create antibody-drug conjugates or to label proteins for imaging studies. This compound is an essential tool for researchers aiming to enhance the efficacy and specificity of their biological studies and therapeutic strategies.

CAS Number
1682653-80-0
Purity
≥ 95% (HPLC)
Molecular Formula
C27H36N9O10
Molecular Weight
604.61
PubChem ID
91757779
Appearance
Red amorphous solid to red oil
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
CAS Number
1682653-80-0
Purity
≥ 95% (HPLC)
Molecular Formula
C27H36N9O10
Molecular Weight
604.61
PubChem ID
91757779
Appearance
Red amorphous solid to red oil
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Tetrazine-PEG5-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is ideal for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules. Its NHS ester functionality allows for efficient coupling, making it valuable in developing targeted therapies.
  • Drug Delivery Systems: The PEG component enhances solubility and biocompatibility, which is crucial for formulating drug delivery systems. This makes it particularly useful in pharmaceutical applications where controlled release is desired.
  • Fluorescent Labeling: Researchers can use this compound to label biomolecules for imaging studies. The tetrazine moiety facilitates rapid and specific reactions with various fluorescent probes, aiding in real-time tracking of biological processes.
  • Diagnostics: In the field of diagnostics, it can be employed to create assays that detect specific biomarkers. Its ability to form stable conjugates enhances the sensitivity and specificity of diagnostic tests.
  • Protein Engineering: This compound is beneficial in modifying proteins to study their function or to create novel proteins with desired properties. The versatility of the PEG chain allows for fine-tuning of the protein's characteristics.

Citations