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Catalog Number:
35081
CAS Number:
1621096-79-4
TCO-PEG4-NHS ester
Purity:
≥ 98% (HPLC)
Synonym(s):
trans-Cyclooctene-PEG4-NHS-ester
Documents
$180.70 /5MG
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Product Information

TCO-PEG4-NHS ester is a versatile and highly functional compound widely utilized in bioconjugation applications. This chemical is particularly valued for its ability to facilitate the attachment of biomolecules, such as peptides and proteins, to various surfaces or other molecules, enhancing the development of targeted drug delivery systems and diagnostic tools. Its unique structure, featuring a PEG (polyethylene glycol) moiety, provides excellent solubility and biocompatibility, making it an ideal choice for researchers in the fields of pharmaceuticals and biotechnology.

The NHS (N-hydroxysuccinimide) functionality allows for efficient coupling reactions, ensuring stable linkages that are crucial for the integrity of bioconjugates. This compound is especially beneficial in the creation of antibody-drug conjugates (ADCs) and other therapeutic agents, where precise targeting is essential for maximizing efficacy while minimizing side effects. With its robust performance and ease of use, TCO-PEG4-NHS ester stands out as a preferred reagent for professionals seeking to innovate in drug development and molecular biology.

Synonyms
trans-Cyclooctene-PEG4-NHS-ester
CAS Number
1621096-79-4
Purity
≥ 98% (HPLC)
Molecular Formula
C24H38N2O10
Molecular Weight
514.57
MDL Number
MFCD28118912
PubChem ID
137796268
Appearance
Colorless oil
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
Synonyms
trans-Cyclooctene-PEG4-NHS-ester
CAS Number
1621096-79-4
Purity
≥ 98% (HPLC)
Molecular Formula
C24H38N2O10
Molecular Weight
514.57
MDL Number
MFCD28118912
PubChem ID
137796268
Appearance
Colorless oil
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

TCO-PEG4-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is ideal for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the development of targeted therapies and diagnostics.
  • Drug Delivery Systems: Its ability to form stable linkages makes it useful in creating advanced drug delivery systems that improve the efficacy and specificity of therapeutic agents.
  • Fluorescent Labeling: Researchers can use TCO-PEG4-NHS ester for fluorescent labeling of biomolecules, facilitating real-time tracking in live-cell imaging and other biological studies.
  • Polymer Chemistry: This compound serves as a valuable building block in polymer synthesis, allowing for the creation of functionalized polymers with tailored properties for various applications.
  • Diagnostics Development: It plays a crucial role in the development of diagnostic tools, enabling the creation of assays that can detect specific biomolecules with high sensitivity and specificity.

Citations