Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
35066
CAS Number:
1480516-75-3
DBCO-PEG4-maleimide
Purity:
≥ 98% (HPLC)
Synonym(s):
Dibenzocyclooctyne-PEG4-maleimide
Documents
$140.20 /5MG
Pack Size Availability Price
Request Bulk Quote
Product Information

DBCO-PEG4-maleimide is a versatile compound widely utilized in bioconjugation and drug delivery applications. This compound features a unique structure that allows for efficient and selective coupling with thiol-containing biomolecules, making it an essential tool for researchers in the fields of biochemistry and molecular biology. Its PEG4 linker enhances solubility and biocompatibility, facilitating the development of stable conjugates that can be used in therapeutic and diagnostic applications.

In practical terms, DBCO-PEG4-maleimide is particularly valuable in the creation of antibody-drug conjugates (ADCs), where it can be employed to attach cytotoxic drugs to antibodies, thereby improving the targeted delivery of therapeutics to cancer cells. Additionally, it is used in the development of fluorescent probes for imaging applications, allowing for real-time tracking of biological processes. The compound's ability to form stable conjugates while maintaining biological activity makes it a preferred choice for researchers looking to enhance the efficacy of their biomolecular constructs.

Synonyms
Dibenzocyclooctyne-PEG4-maleimide
CAS Number
1480516-75-3
Purity
≥ 98% (HPLC)
Molecular Formula
C36H42N4O9
Molecular Weight
674.74
MDL Number
MFCD22572659
PubChem ID
86580488
Appearance
Slightly orange oil or waxy solid
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
Synonyms
Dibenzocyclooctyne-PEG4-maleimide
CAS Number
1480516-75-3
Purity
≥ 98% (HPLC)
Molecular Formula
C36H42N4O9
Molecular Weight
674.74
MDL Number
MFCD22572659
PubChem ID
86580488
Appearance
Slightly orange oil or waxy solid
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

DBCO-PEG4-maleimide is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for linking biomolecules, such as proteins and antibodies, to various targets. Its unique reactivity allows for precise conjugation, enhancing the efficacy of therapeutic agents.
  • Drug Delivery Systems: DBCO-PEG4-maleimide is used in the development of advanced drug delivery systems. By attaching drugs to this compound, researchers can improve the solubility and stability of pharmaceuticals, leading to better patient outcomes.
  • Diagnostics: In the field of diagnostics, this chemical aids in the creation of imaging agents. Its ability to form stable linkages with imaging probes enhances the sensitivity and specificity of diagnostic tests.
  • Nanotechnology: DBCO-PEG4-maleimide plays a crucial role in the fabrication of nanoparticles for targeted therapy. Its properties allow for the customization of nanoparticles, making them effective carriers for targeted drug delivery.
  • Research and Development: This compound is widely used in academic and industrial research settings for developing new materials and studying biological processes. Its versatility makes it a valuable tool for scientists exploring innovative applications.

Citations