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Catalog Number:
35048
CAS Number:
1400191-52-7
DBCO-sulfo-NHS Ester
Purity:
≥ 95% (HPLC)
Synonym(s):
Dibenzocyclooctyne-C6-Sulfo-NHS ester
Documents
$140.20 /5MG
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Product Information

DBCO-sulfo-NHS dster is a versatile compound widely utilized in bioconjugation and drug delivery applications. This sulfonated derivative of DBCO (dibenzocyclooctyne) features a unique structure that enhances its solubility and reactivity, making it an ideal choice for researchers looking to facilitate efficient labeling and conjugation processes. Its ability to form stable linkages with biomolecules, such as proteins and nucleic acids, allows for the development of targeted therapies and diagnostic tools.

In the pharmaceutical and biotechnology industries, DBCO-sulfo-NHS dster is particularly valuable for creating antibody-drug conjugates (ADCs) and other bioconjugates that require precise control over the attachment of therapeutic agents. Its application in click chemistry provides a reliable method for synthesizing complex biomolecular constructs, which can lead to improved efficacy and reduced side effects in therapeutic applications. Researchers can leverage this compound to streamline their workflows and enhance the performance of their bioconjugates, ultimately contributing to advancements in targeted therapies and personalized medicine.

Synonyms
Dibenzocyclooctyne-C6-Sulfo-NHS ester
CAS Number
1400191-52-7
Purity
≥ 95% (HPLC)
Molecular Formula
C25H21N2NaO8S
Molecular Weight
532.5
PubChem ID
77078153
Appearance
White to slightly grey crystalline
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
Synonyms
Dibenzocyclooctyne-C6-Sulfo-NHS ester
CAS Number
1400191-52-7
Purity
≥ 95% (HPLC)
Molecular Formula
C25H21N2NaO8S
Molecular Weight
532.5
PubChem ID
77078153
Appearance
White to slightly grey crystalline
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

DBCO-sulfo-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for linking biomolecules, such as proteins or antibodies, to other molecules like fluorophores or drugs, enhancing their functionality in therapeutic applications.
  • Drug Development: In pharmaceutical research, it aids in the design of targeted drug delivery systems, allowing for more effective treatments with reduced side effects.
  • Diagnostics: It is used in the development of diagnostic assays, where it helps in the attachment of detection agents to biological samples, improving sensitivity and accuracy.
  • Nanotechnology: The compound plays a crucial role in the functionalization of nanoparticles, enabling their use in imaging and targeted therapy in cancer treatment.
  • Research Tools: It serves as a valuable reagent in chemical biology, facilitating the study of protein interactions and cellular processes through effective tagging and visualization techniques.

Citations