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Catalog Number:
33620
CAS Number:
854300-32-6
Fmoc-D-2,6-dimethyltyrosine
Purity:
≥ 99% (Chiral HPLC, HPLC)
Synonym(s):
Fmoc-D-Tyr(2,6-DiCH3)-OH, (R)-Fmoc-2-amino-3-(2,6-dimethyl-3-hydroxyphenyl)propionic acid
Documents
$110.00 /100MG
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Product Information

Fmoc-D-2,6-dimethyltyrosine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which facilitates the selective protection of the amino group during solid-phase peptide synthesis, making it an essential building block for researchers in the field of medicinal chemistry. Its unique structure, characterized by the presence of two methyl groups on the aromatic ring, enhances its hydrophobic properties, which can improve the stability and bioavailability of peptides in various formulations.

In practical applications, Fmoc-D-2,6-dimethyltyrosine is particularly valuable in the synthesis of bioactive peptides and proteins, where it can contribute to the design of therapeutics with enhanced efficacy and reduced side effects. Its ability to mimic natural amino acids while providing additional functional benefits makes it a preferred choice among chemists and biochemists. Researchers can leverage this compound to explore novel drug candidates, optimize peptide sequences, and develop targeted therapies in areas such as oncology and neurology.

Synonyms
Fmoc-D-Tyr(2,6-DiCH3)-OH, (R)-Fmoc-2-amino-3-(2,6-dimethyl-3-hydroxyphenyl)propionic acid
CAS Number
854300-32-6
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C26H25NO5
Molecular Weight
431.48
MDL Number
MFCD09752873
PubChem ID
53427534
Appearance
Off-white powder
Optical Rotation
[a]D25 = 23 ± 2 ° (C=1 in DMF)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-D-Tyr(2,6-DiCH3)-OH, (R)-Fmoc-2-amino-3-(2,6-dimethyl-3-hydroxyphenyl)propionic acid
CAS Number
854300-32-6
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C26H25NO5
Molecular Weight
431.48
MDL Number
MFCD09752873
PubChem ID
53427534
Appearance
Off-white powder
Optical Rotation
[a]D25 = 23 ± 2 ° (C=1 in DMF)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-2,6-dimethyltyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Its unique structure aids in the design of novel pharmaceuticals, particularly in creating compounds that target specific receptors in the body, enhancing drug efficacy.
  • Bioconjugation: The compound is employed in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in developing diagnostic tools and therapeutics.
  • Research in Neuroscience: It is used in studies related to neurotransmitter pathways, helping researchers understand the role of modified amino acids in brain function and behavior.
  • Protein Engineering: The compound is valuable in modifying proteins to enhance their stability and activity, which is essential in biotechnology applications, including enzyme production and therapeutic protein development.

Citations