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Catalog Number:
33614
CAS Number:
1217751-18-2
Fmoc-4-acetyl-D-phenylalanine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-Phe(4-Ac)-OH, (R)-Fmoc-2-amino-3-(4-acetylphenyl)propionic acid
Documents
$95.00 /25MG
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Product Information

Fmoc-4-acetyl-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the acetyl group on the phenyl ring, enhances its reactivity and compatibility with various coupling reagents, making it an ideal choice for researchers in the fields of medicinal chemistry and biochemistry.

In practical applications, Fmoc-4-acetyl-D-phenylalanine serves as a building block in the synthesis of biologically active peptides, including those with therapeutic potential in treating various diseases. Its ability to facilitate the formation of peptide bonds while maintaining stability under standard reaction conditions makes it a preferred choice for professionals looking to streamline their synthesis processes. Additionally, its high purity and consistent performance ensure reliable results in research and development settings, making it an invaluable asset for laboratories focused on peptide-based drug discovery.

Synonyms
Fmoc-D-Phe(4-Ac)-OH, (R)-Fmoc-2-amino-3-(4-acetylphenyl)propionic acid
CAS Number
1217751-18-2
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C26H23NO5
Molecular Weight
429.47
MDL Number
MFCD12198181
PubChem ID
21908899
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 8 ± 1 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-D-Phe(4-Ac)-OH, (R)-Fmoc-2-amino-3-(4-acetylphenyl)propionic acid
CAS Number
1217751-18-2
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C26H23NO5
Molecular Weight
429.47
MDL Number
MFCD12198181
PubChem ID
21908899
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 8 ± 1 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-acetyl-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides used in various biological applications.
  • Drug Development: Its unique structure aids in the design of peptide-based drugs, which can target specific biological pathways, enhancing the efficacy of therapeutic agents in treating diseases.
  • Bioconjugation: The chemical is used to create bioconjugates, linking peptides to other biomolecules like antibodies or drugs, improving their delivery and effectiveness in targeted therapies.
  • Research in Neuroscience: It is employed in studies related to neuropeptides, contributing to the understanding of neural signaling and potential treatments for neurological disorders.
  • Custom Peptide Libraries: Researchers utilize this compound to generate diverse peptide libraries for screening potential drug candidates, facilitating the discovery of new therapeutic agents.

Citations