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Catalog Number:
33580
CAS Number:
1231709-22-0
Fmoc-(R)-2-Amino-2-methylbutyric acid
Purity:
≥ 99% (Chiral HPLC)
Synonym(s):
Fmoc-D-Isovaline
Documents
$58.39 /100MG
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Product Information

Fmoc-(R)-2-Amino-2-methylbutyric acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during solid-phase peptide synthesis. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers aiming to develop complex peptides with high purity and yield. The (R)-configuration of this amino acid enhances its biological activity, making it particularly relevant in the design of pharmaceuticals and biologically active compounds.

In addition to its applications in peptide synthesis, Fmoc-(R)-2-Amino-2-methylbutyric acid serves as a valuable intermediate in the production of various bioactive molecules. Its stability and compatibility with a range of coupling reagents make it a preferred choice in both academic and industrial settings. Researchers can leverage this compound to streamline their synthesis processes, ultimately leading to more efficient drug discovery and development. With its proven track record in enhancing peptide synthesis, this compound is an essential tool for any laboratory focused on advancing medicinal chemistry.

Synonyms
Fmoc-D-Isovaline
CAS Number
1231709-22-0
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C20H21NO4
Molecular Weight
339.39
MDL Number
MFCD12031689
PubChem ID
73006883
Appearance
White powder
Optical Rotation
[a]20D = -3 ± 1 ° (C=1 in DCM)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-D-Isovaline
CAS Number
1231709-22-0
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C20H21NO4
Molecular Weight
339.39
MDL Number
MFCD12031689
PubChem ID
73006883
Appearance
White powder
Optical Rotation
[a]20D = -3 ± 1 ° (C=1 in DCM)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-2-Amino-2-methylbutyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: Its application in drug design helps in creating more effective therapeutic agents by modifying peptide sequences, which can enhance their stability and bioactivity.
  • Biotechnology: In the field of biotechnology, it is used to create peptide-based vaccines and therapeutics, offering a pathway to develop targeted treatments for various diseases.
  • Research in Neuroscience: Researchers utilize this compound to study neuropeptides, which play a significant role in brain function and behavior, potentially leading to breakthroughs in understanding neurological disorders.
  • Custom Peptide Libraries: The compound is essential for generating custom peptide libraries for high-throughput screening, enabling researchers to discover new drug candidates efficiently.

Citations