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Catalog Number:
33523
CAS Number:
1892-57-5
N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide
Purity:
≥ 98% (GC)
Synonym(s):
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide
Hazmat
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Product Information

N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide is a versatile coupling agent widely utilized in peptide synthesis and bioconjugation processes. This compound is particularly valued in the fields of organic chemistry and biochemistry for its ability to activate carboxylic acids, facilitating the formation of amide bonds with high efficiency. Its unique structure enhances reactivity, making it an ideal choice for researchers looking to streamline their synthesis protocols.

In addition to its applications in peptide synthesis, N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide is also employed in the development of various biomaterials and drug delivery systems. Its effectiveness in promoting covalent linkages between biomolecules allows for the creation of stable conjugates, which are essential in the development of targeted therapies and diagnostics. Researchers appreciate its ease of use and compatibility with a wide range of functional groups, making it a preferred choice over other coupling agents in many applications.

Synonyms
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide
CAS Number
1892-57-5
Purity
≥ 98% (GC)
Molecular Formula
C8H17N3
Molecular Weight
155.24
MDL Number
MFCD00044916
PubChem ID
15908
Density
0.877 g/mL at 20 ?C (Lit.)
Appearance
Colorless to light yellow liquid
Boiling Point
100 - 105 ?C / 2 mmHg
Refractive Index
n20/D 1.459 - 1.465 (Lit.)
Conditions
Store at -10 °C
General Information
Synonyms
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide
CAS Number
1892-57-5
Purity
≥ 98% (GC)
Molecular Formula
C8H17N3
Molecular Weight
155.24
MDL Number
MFCD00044916
PubChem ID
15908
Density
0.877 g/mL at 20 ?C (Lit.)
Appearance
Colorless to light yellow liquid
Boiling Point
100 - 105 ?C / 2 mmHg
Refractive Index
n20/D 1.459 - 1.465 (Lit.)
Conditions
Store at -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key reagent in the formation of peptide bonds, facilitating the coupling of amino acids in the development of peptides and proteins, which are essential in pharmaceuticals and biotechnology.
  • Bioconjugation: It is commonly used to link biomolecules, such as proteins to antibodies or drugs, enhancing the efficacy of targeted therapies in drug development and diagnostics.
  • Polymer Chemistry: The chemical serves as a coupling agent in the synthesis of various polymers, improving their properties for applications in materials science and engineering.
  • Cross-linking Agents: It acts as a cross-linker in the preparation of hydrogels, which are vital in tissue engineering and drug delivery systems, offering controlled release of therapeutic agents.
  • Surface Modification: This compound is employed in modifying surfaces of biomaterials to enhance biocompatibility, crucial for medical implants and devices.

Citations