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Catalog Number:
33492
CAS Number:
2044709-96-6
Fmoc-D-Phe(4-guanidino-Boc2)-OH
Purity:
≥ 99.7% (Chiral HPLC)
Synonym(s):
Fmoc-4-(N,N'-di-Boc-guanidino)-D-phenylalanine
Documents
$70.00 /100MG
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Product Information

Fmoc-D-Phe(4-guanidino-Boc2)-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry for its ability to facilitate the formation of peptide bonds, making it an essential building block for the synthesis of complex peptides and proteins. Its unique structure, featuring both Fmoc and Boc protecting groups, allows for selective deprotection, providing researchers with enhanced control during synthesis. This compound is widely used in the development of peptide-based therapeutics, particularly in the design of inhibitors and modulators for various biological targets.

In addition to its applications in drug discovery, Fmoc-D-Phe(4-guanidino-Boc2)-OH is also utilized in the study of protein interactions and the development of biomaterials. Its stability and compatibility with various coupling reagents make it an ideal choice for researchers looking to explore new therapeutic avenues. With its robust properties and versatility, this compound stands out as a valuable asset in both academic and industrial research settings.

Synonyms
Fmoc-4-(N,N'-di-Boc-guanidino)-D-phenylalanine
CAS Number
2044709-96-6
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C35H40N4O8
Molecular Weight
644.7
MDL Number
MFCD30475918
PubChem ID
135480908
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -12 ±1 °(C=1 in MeOH)
Conditions
Store at ≤ -20 °C
General Information
Synonyms
Fmoc-4-(N,N'-di-Boc-guanidino)-D-phenylalanine
CAS Number
2044709-96-6
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C35H40N4O8
Molecular Weight
644.7
MDL Number
MFCD30475918
PubChem ID
135480908
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -12 ±1 °(C=1 in MeOH)
Conditions
Store at ≤ -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-Phe(4-guanidino-Boc2)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of therapeutic agents. Its protective groups facilitate selective reactions, enhancing the efficiency of peptide assembly.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs. The unique structure allows for modifications that can improve bioactivity and specificity, making it valuable in designing new treatments.
  • Bioconjugation: This chemical is employed in bioconjugation processes, linking peptides to other biomolecules. This application is crucial in creating targeted drug delivery systems, improving the efficacy of treatments.
  • Research in Cancer Therapeutics: Its role in developing peptide inhibitors is significant in cancer research. By modifying its structure, researchers can create compounds that selectively target cancer cells, offering potential new therapies.
  • Diagnostics: The compound is also used in the development of diagnostic tools. Its ability to form specific interactions with biomolecules aids in creating sensitive assays for disease detection.

Citations