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Catalog Number:
33491
CAS Number:
2250437-39-7
Nα -Fmoc- Nε-(2-nitrobenzenesulfonyl)-D-lysine
Purity:
≥ 98% (HPLC)
Synonym(s):
-Fmoc--Nosyl-D-lysine, Fmoc-D-Lys(Ns)-OH
Documents
$95.00 /100MG
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Product Information

Na -Fmoc- Ne-(2-nitrobenzenesulfonyl)-D-lysine is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a protective Fmoc group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis. Its unique sulfonyl group enhances the compound's reactivity, making it an excellent choice for researchers looking to create complex peptide structures with improved stability and bioactivity. The incorporation of the nitrobenzenesulfonyl moiety allows for specific targeting in biochemical applications, providing researchers with a powerful tool for studying protein interactions and enzyme activity.

In addition to its applications in peptide synthesis, Na -Fmoc- Ne-(2-nitrobenzenesulfonyl)-D-lysine is also valuable in the development of therapeutic agents, particularly in the fields of oncology and neurology. Its ability to modify peptide sequences can lead to the creation of novel compounds with enhanced pharmacological properties. This compound stands out for its ease of use and effectiveness in producing high-purity peptides, making it a preferred choice for both academic and industrial laboratories focused on drug discovery and development.

Synonyms
-Fmoc--Nosyl-D-lysine, Fmoc-D-Lys(Ns)-OH
CAS Number
2250437-39-7
Purity
≥ 98% (HPLC)
Molecular Formula
C27H27N3O8S
Molecular Weight
553.6
MDL Number
MFCD31380698
PubChem ID
138109651
Appearance
Light yellow powder
Optical Rotation
[a]20D = 10 ± 2 º (C=1 in DMF)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
-Fmoc--Nosyl-D-lysine, Fmoc-D-Lys(Ns)-OH
CAS Number
2250437-39-7
Purity
≥ 98% (HPLC)
Molecular Formula
C27H27N3O8S
Molecular Weight
553.6
MDL Number
MFCD31380698
PubChem ID
138109651
Appearance
Light yellow powder
Optical Rotation
[a]20D = 10 ± 2 º (C=1 in DMF)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na -Fmoc- Ne-(2-nitrobenzenesulfonyl)-D-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various reaction conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, it is used to create novel peptide-based drugs, particularly those targeting specific receptors. The unique properties of this compound enhance the bioactivity of therapeutic peptides.
  • Bioconjugation: This chemical is valuable in bioconjugation processes, where it can facilitate the attachment of peptides to other biomolecules, such as antibodies or enzymes, improving their functionality in diagnostic and therapeutic applications.
  • Protein Engineering: Researchers utilize it to modify lysine residues in proteins, which can alter protein function and stability. This application is crucial in developing proteins with tailored properties for industrial and therapeutic use.
  • Analytical Chemistry: It is employed in the development of analytical methods for detecting and quantifying peptides in complex mixtures, aiding in quality control and research applications.

Citations