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Catalog Number:
33489
CAS Number:
1159531-18-6
Nα-Fmoc- Nβ -4-pentynoyl-L-lysine
Purity:
≥ 99% (HPLC, TLC)
Synonym(s):
Fmoc-L-Lys(Pentynoyl)-OH, (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-6-(pent-4-ynamido)hexanoic acid
Documents
$60.40 /100MG
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Product Information

Na-Fmoc-Nb-4-pentynoyl-L-lysine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely recognized for its effectiveness in solid-phase peptide synthesis. The unique pentynoyl side chain enhances its reactivity and allows for the incorporation of alkyne functionalities, making it an excellent choice for applications in click chemistry and bioconjugation. Researchers and industry professionals can leverage this compound to create complex peptides and proteins with precise modifications, facilitating advancements in therapeutic development and biomolecular research.

The compound's stability and compatibility with various coupling reagents make it a preferred choice for those looking to streamline their synthesis processes. Its ability to undergo selective reactions opens up new avenues for the development of innovative drug candidates and diagnostic tools. With Na-Fmoc-Nb-4-pentynoyl-L-lysine, professionals can enhance their research capabilities and achieve greater efficiency in their projects.

Synonyms
Fmoc-L-Lys(Pentynoyl)-OH, (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-6-(pent-4-ynamido)hexanoic acid
CAS Number
1159531-18-6
Purity
≥ 99% (HPLC, TLC)
Molecular Formula
C26H28N2O5
Molecular Weight
448.5
MDL Number
MFCD00027297
PubChem ID
89560985
Melting Point
107 - 113 °C
Appearance
White crystalline powder
Optical Rotation
[a]20D = -13 ± 1 ° (C=1 in DMF)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-L-Lys(Pentynoyl)-OH, (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-6-(pent-4-ynamido)hexanoic acid
CAS Number
1159531-18-6
Purity
≥ 99% (HPLC, TLC)
Molecular Formula
C26H28N2O5
Molecular Weight
448.5
MDL Number
MFCD00027297
PubChem ID
89560985
Melting Point
107 - 113 °C
Appearance
White crystalline powder
Optical Rotation
[a]20D = -13 ± 1 ° (C=1 in DMF)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc- Nb -4-pentynoyl-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with specific functionalities, which is crucial in drug development.
  • Bioconjugation: It can be employed in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, enhancing the effectiveness of targeted therapies in medicine.
  • Drug Delivery Systems: The compound's unique properties make it suitable for developing drug delivery systems, improving the bioavailability and targeted delivery of therapeutic agents.
  • Research in Cancer Therapy: It plays a role in cancer research by enabling the design of novel peptide-based drugs that can selectively target cancer cells, potentially leading to more effective treatments with fewer side effects.
  • Material Science: In material science, it can be used to modify polymers, enhancing their properties for applications in biomedical devices and other advanced materials.

Citations