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Catalog Number:
33478
CAS Number:
1807631-13-5
(R)-2-Azido-3-(Fmoc-amino)propanoic acid
Purity:
≥ 99.7% (Chiral HPLC)
Synonym(s):
N3-D-Dap(Fmoc)-OH, Azido-D-Dap(Fmoc)-OH
Documents
$80.00 /100MG
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Product Information

(R)-2-Azido-3-(Fmoc-amino)propanoic acid is a versatile building block in peptide synthesis and medicinal chemistry, known for its unique azido functional group that allows for click chemistry applications. This compound is particularly valuable in the development of peptide-based therapeutics and bioconjugates, where the Fmoc protecting group facilitates selective deprotection during synthesis. Its azido group can participate in various coupling reactions, making it an essential tool for researchers looking to create complex molecular architectures with precision.

The compound's stability and reactivity make it suitable for a range of applications, including drug discovery, where it can be used to modify peptides for enhanced biological activity or specificity. Additionally, (R)-2-Azido-3-(Fmoc-amino)propanoic acid can serve as a precursor for the synthesis of more complex molecules, expanding its utility in pharmaceutical research and development. Its ability to undergo straightforward transformations while maintaining structural integrity positions it as a preferred choice for professionals in the field.

Synonyms
N3-D-Dap(Fmoc)-OH, Azido-D-Dap(Fmoc)-OH
CAS Number
1807631-13-5
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C18H16N4O4
Molecular Weight
352.3
MDL Number
MFCD22989450
PubChem ID
72988743
Melting Point
148 - 152 °C
Appearance
White crystalline powder
Optical Rotation
[a]20D
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N3-D-Dap(Fmoc)-OH, Azido-D-Dap(Fmoc)-OH
CAS Number
1807631-13-5
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C18H16N4O4
Molecular Weight
352.3
MDL Number
MFCD22989450
PubChem ID
72988743
Melting Point
148 - 152 °C
Appearance
White crystalline powder
Optical Rotation
[a]20D
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-2-Azido-3-(Fmoc-amino)propanoic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the efficiency and yield of the process.
  • Bioconjugation: It is employed in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other molecules, which is essential in drug development and diagnostics.
  • Fluorescent Probes: The azido group can be used for labeling and imaging in biological systems, making it valuable in the development of fluorescent probes for cellular studies.
  • Click Chemistry: This compound is compatible with click chemistry reactions, facilitating the rapid and selective formation of complex molecules, which is beneficial in materials science and medicinal chemistry.
  • Drug Development: Its unique structure allows for modifications that can lead to the discovery of new therapeutic agents, providing an advantage in creating targeted treatments.

Citations