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Catalog Number:
33470
CAS Number:
134179-38-7
N3-PEG(4)-NH2
Purity:
≥ 97% (Assay by titration)
Synonym(s):
Amino-PEG3-azide, Azido-PEG3-amine
Documents
$50.30 /100MG
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Product Information

N3-PEG(4)-NH2 is a versatile polyethylene glycol derivative that features an azide functional group, making it an essential compound for various applications in bioconjugation and drug delivery. This compound is particularly valuable in the fields of biochemistry and molecular biology, where it serves as a linker for attaching biomolecules, such as proteins or peptides, to surfaces or other molecules. Its unique structure allows for efficient conjugation reactions, facilitating the development of targeted therapies and diagnostic tools. Researchers appreciate N3-PEG(4)-NH2 for its hydrophilicity, which enhances solubility and stability in biological environments, thereby improving the pharmacokinetics of conjugated drugs.

In addition to its use in drug delivery systems, N3-PEG(4)-NH2 is also employed in the synthesis of hydrogels and other biomaterials, providing a scaffold for tissue engineering applications. Its ability to participate in click chemistry reactions further expands its utility, enabling the creation of complex molecular architectures with precision. With its broad range of applications and favorable properties, N3-PEG(4)-NH2 is an invaluable tool for researchers and industry professionals looking to innovate in the fields of drug development and biomaterials.

Synonyms
Amino-PEG3-azide, Azido-PEG3-amine
CAS Number
134179-38-7
Purity
≥ 97% (Assay by titration)
Molecular Formula
C8H18N4O3
Molecular Weight
218.3
MDL Number
MFCD20134134
PubChem ID
2735280
Appearance
Light yellow oil
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Amino-PEG3-azide, Azido-PEG3-amine
CAS Number
134179-38-7
Purity
≥ 97% (Assay by titration)
Molecular Formula
C8H18N4O3
Molecular Weight
218.3
MDL Number
MFCD20134134
PubChem ID
2735280
Appearance
Light yellow oil
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N3-PEG(4)-NH2 is widely utilized in research focused on various applications:

  • Bioconjugation: This compound serves as an effective linker in bioconjugation processes, allowing researchers to attach biomolecules like proteins or antibodies to surfaces or other molecules, enhancing the functionality of diagnostic and therapeutic agents.
  • Drug Delivery Systems: N3-PEG(4)-NH2 is used in the development of drug delivery systems, improving the solubility and stability of pharmaceuticals, which leads to better therapeutic outcomes and reduced side effects.
  • Gene Delivery: In gene therapy, this compound facilitates the delivery of nucleic acids into cells, promoting efficient gene transfer and expression, which is crucial for developing treatments for genetic disorders.
  • Surface Modification: It is applied in modifying surfaces of biomaterials to enhance biocompatibility and reduce immunogenicity, making it valuable in the fields of tissue engineering and regenerative medicine.
  • Fluorescent Labeling: The azide group in N3-PEG(4)-NH2 allows for specific labeling with fluorescent dyes, enabling researchers to track and visualize biological processes in real-time, which is essential for cellular and molecular biology studies.

Citations