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Catalog Number:
33463
CAS Number:
2250437-44-4
Nα-Fmoc- Nβ-(propargyloxy)carbonyl-L-2,3-diaminopropionic acid
Purity:
99 - 100% (Assay by titration)
Synonym(s):
Fmoc-L-Dap(Poc)-OH, (S-1-(9H-Fluoren-9-yl)-3,8-dioxo-2,9-dioxa-4,7-diazadodec-11-yne-5-carboxylic acid
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$127.79 /100MG
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Product Information

Na-Fmoc-Nb-(propargyloxy)carbonyl-L-2,3-diaminopropionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a unique Fmoc (fluorenylmethyloxycarbonyl) protecting group, which is essential for the selective protection of amines during the synthesis of complex peptides. Its propargyloxycarbonyl moiety enhances its reactivity, making it an excellent candidate for click chemistry applications, particularly in the development of bioconjugates and drug delivery systems. Researchers appreciate its stability under various conditions, which facilitates streamlined synthetic processes and improves yields.

This compound is particularly valuable in the pharmaceutical industry, where it plays a crucial role in the design of novel therapeutics. Its ability to form stable linkages with other biomolecules allows for the creation of targeted drug delivery systems, enhancing the efficacy of treatments. Additionally, Na-Fmoc-Nb-(propargyloxy)carbonyl-L-2,3-diaminopropionic acid is instrumental in the development of peptide-based vaccines and diagnostics, showcasing its broad applicability in advancing healthcare solutions.

Synonyms
Fmoc-L-Dap(Poc)-OH, (S-1-(9H-Fluoren-9-yl)-3,8-dioxo-2,9-dioxa-4,7-diazadodec-11-yne-5-carboxylic acid
CAS Number
2250437-44-4
Purity
99 - 100% (Assay by titration)
Molecular Formula
C22H20N2O6
Molecular Weight
408.4
MDL Number
MFCD31380700
PubChem ID
170999913
Melting Point
142 - 148 ?C
Appearance
White crystalline powder
Optical Rotation
[a]20D = -9 ± 1 ° (C=1 in MeOH)
Conditions
Store at 2-8 °C
General Information
Synonyms
Fmoc-L-Dap(Poc)-OH, (S-1-(9H-Fluoren-9-yl)-3,8-dioxo-2,9-dioxa-4,7-diazadodec-11-yne-5-carboxylic acid
CAS Number
2250437-44-4
Purity
99 - 100% (Assay by titration)
Molecular Formula
C22H20N2O6
Molecular Weight
408.4
MDL Number
MFCD31380700
PubChem ID
170999913
Melting Point
142 - 148 ?C
Appearance
White crystalline powder
Optical Rotation
[a]20D = -9 ± 1 ° (C=1 in MeOH)
Conditions
Store at 2-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc- Nb-(propargyloxy)carbonyl-L-2,3-diaminopropionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with specific functionalities.
  • Drug Development: It is used in the development of novel pharmaceuticals, particularly in designing compounds that can target specific biological pathways.
  • Bioconjugation: The unique functional groups present enable effective bioconjugation techniques, which are essential in creating targeted drug delivery systems.
  • Material Science: This chemical is applied in the development of advanced materials, particularly in creating polymers with enhanced properties for various industrial applications.
  • Diagnostics: It plays a role in the formulation of diagnostic agents, improving the sensitivity and specificity of detection methods in medical diagnostics.

Citations