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Catalog Number:
33458
CAS Number:
650601-59-5
Boc-(4R-4-azido-D-proline
Purity:
≥ 99% (Assay by titration, HPLC)
Synonym(s):
Boc-D-Pro(4-N3) (2R,4R, Boc-(2R,4R )-4-azidoproline
Antibiotic
Documents
$86.23 /100MG
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Product Information

Boc-(4R)-4-azido-D-proline is a versatile building block in peptide synthesis, particularly valued for its unique azido functional group, which facilitates click chemistry applications. This compound serves as a key intermediate in the development of bioactive peptides and pharmaceuticals, enabling researchers to explore novel therapeutic avenues. Its Boc (tert-butyloxycarbonyl) protecting group enhances stability during synthesis, making it an ideal choice for complex peptide sequences.

In addition to its role in drug discovery, Boc-(4R)-4-azido-D-proline is increasingly utilized in materials science for the development of functionalized polymers and nanomaterials. Its ability to participate in bioorthogonal reactions allows for precise modifications, paving the way for innovative applications in targeted drug delivery and imaging. Researchers and industry professionals can leverage this compound to streamline their synthesis processes while expanding their capabilities in creating advanced materials and therapeutics.

Synonyms
Boc-D-Pro(4-N3) (2R,4R, Boc-(2R,4R )-4-azidoproline
CAS Number
650601-59-5
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C10H16N4O4
Molecular Weight
256.3
MDL Number
MFCD31657286
PubChem ID
14842620
Melting Point
76 - 80 °C
Appearance
White crystalline powder
Optical Rotation
[a]20D = 24 ± 1 ° (C=1 in MeOH)
Conditions
Store at 2-8 °C
General Information
Synonyms
Boc-D-Pro(4-N3) (2R,4R, Boc-(2R,4R )-4-azidoproline
CAS Number
650601-59-5
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C10H16N4O4
Molecular Weight
256.3
MDL Number
MFCD31657286
PubChem ID
14842620
Melting Point
76 - 80 °C
Appearance
White crystalline powder
Optical Rotation
[a]20D = 24 ± 1 ° (C=1 in MeOH)
Conditions
Store at 2-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Boc-(4R)-4-azido-D-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of bioactive peptides that can be used in pharmaceuticals.
  • Drug Development: Its azido group allows for click chemistry applications, facilitating the attachment of various functional groups to create novel drug candidates with enhanced properties.
  • Bioconjugation: The compound is ideal for bioconjugation processes, enabling the linking of biomolecules to therapeutic agents, which is crucial in targeted drug delivery systems.
  • Research in Protein Engineering: It is used in the modification of proteins, allowing researchers to study protein interactions and functions, which is essential in understanding diseases.
  • Material Science: The unique properties of Boc-(4R)-4-azido-D-proline make it valuable in developing new materials with specific chemical functionalities, useful in various industrial applications.

Citations