Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
33455
4R-4-Azido-D-Proline hydrochloride
Purity:
≥ 99% (Assay by titration, HPLC)
Synonym(s):
H-D-Pro(4-N3)·HCl (2R,4R, (2R,4R-4-azidopyrrolidine-2-carboxylic acidhydrochloride
Antibiotic
Documents
$120.88 /25MG
Pack Size Availability Price
Request Bulk Quote
Product Information

(4R)-4-Azido-D-Proline hydrochloride is a valuable compound in the field of chemical research and pharmaceutical development. This unique amino acid derivative features an azido group, which enhances its reactivity and versatility in various applications. Its structural properties make it an essential building block for the synthesis of peptides and proteins, particularly in the development of novel therapeutics and bioconjugates. Researchers often utilize (4R)-4-Azido-D-Proline hydrochloride in click chemistry, enabling the efficient labeling and modification of biomolecules for imaging and drug delivery purposes.

The compound's stability and compatibility with a range of functional groups further enhance its appeal in medicinal chemistry and materials science. Its ability to facilitate the introduction of bioorthogonal functionalities makes it an attractive option for scientists looking to explore new pathways in drug discovery and development. With its growing relevance in the synthesis of complex molecules, (4R)-4-Azido-D-Proline hydrochloride stands out as a key player in advancing research and innovation in various scientific fields.

Synonyms
H-D-Pro(4-N3)·HCl (2R,4R, (2R,4R-4-azidopyrrolidine-2-carboxylic acidhydrochloride
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C5H8N4O2·HCl
Molecular Weight
192.6
Melting Point
147 - 154 °C (Dec.)
Appearance
White crystalline powder
Optical Rotation
[a]20D = -34 ± 1º (C=1 in MeOH)
Conditions
Store at 2-8 °C
General Information
Synonyms
H-D-Pro(4-N3)·HCl (2R,4R, (2R,4R-4-azidopyrrolidine-2-carboxylic acidhydrochloride
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C5H8N4O2·HCl
Molecular Weight
192.6
Melting Point
147 - 154 °C (Dec.)
Appearance
White crystalline powder
Optical Rotation
[a]20D = -34 ± 1º (C=1 in MeOH)
Conditions
Store at 2-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

(4R)-4-Azido-D-Proline hydrochloride is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in creating modified peptides that can enhance biological activity or stability.
  • Bioconjugation: Its azido group allows for click chemistry applications, enabling researchers to attach various biomolecules, such as fluorescent tags or drugs, to proteins or other macromolecules efficiently.
  • Drug Development: In medicinal chemistry, it plays a role in the design of new pharmaceuticals, especially in developing compounds targeting specific biological pathways.
  • Protein Labeling: The unique properties of this compound facilitate the labeling of proteins for imaging studies, aiding in the visualization of cellular processes in real-time.
  • Research in Neuroscience: It is used in studies related to neurobiology, helping to investigate the role of specific peptides in neuronal signaling and function.

Citations