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Catalog Number:
33411
CAS Number:
1353016-71-3
DBCO-NHS ester
Purity:
≥ 97% (Assay)
Synonym(s):
11,12-Didehydro-oxo-Dibenz[b,f]azocine-5(6H)-butanoic acid2,5-dioxo-1-pyrrolidinyl ester
Documents
$140.00 /5MG
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Product Information

DBCO-NHS ester is a versatile and highly functional chemical compound widely utilized in bioconjugation and labeling applications. This compound features a unique structure that allows for efficient coupling with various biomolecules, making it an invaluable tool for researchers in the fields of biochemistry and molecular biology. Its ability to form stable linkages with amines and other nucleophiles enhances its utility in the development of targeted drug delivery systems, diagnostic agents, and imaging probes.

Researchers appreciate DBCO-NHS ester for its rapid reaction kinetics and compatibility with a range of biological systems, which facilitates the creation of complex biomolecular constructs. This compound is particularly advantageous in the synthesis of antibody-drug conjugates (ADCs) and other therapeutic modalities, where precise control over the conjugation process is essential. With its robust performance and ease of use, DBCO-NHS ester stands out as a preferred choice for professionals seeking reliable solutions in chemical biology and pharmaceutical development.

Synonyms
11,12-Didehydro-oxo-Dibenz[b,f]azocine-5(6H)-butanoic acid2,5-dioxo-1-pyrrolidinyl ester
CAS Number
1353016-71-3
Purity
≥ 97% (Assay)
Molecular Formula
C23H18N2O5
Molecular Weight
402.4
MDL Number
MFCD24386367
PubChem ID
77078178
Appearance
Pink or slightly yellow to gray solid/powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
11,12-Didehydro-oxo-Dibenz[b,f]azocine-5(6H)-butanoic acid2,5-dioxo-1-pyrrolidinyl ester
CAS Number
1353016-71-3
Purity
≥ 97% (Assay)
Molecular Formula
C23H18N2O5
Molecular Weight
402.4
MDL Number
MFCD24386367
PubChem ID
77078178
Appearance
Pink or slightly yellow to gray solid/powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

DBCO-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for attaching biomolecules, such as proteins or nucleic acids, to surfaces or other molecules, enabling the development of targeted therapies and diagnostics.
  • Drug Development: In pharmaceutical research, DBCO-NHS ester facilitates the creation of drug conjugates, improving the efficacy and specificity of treatments for various diseases, including cancer.
  • Fluorescent Labeling: Researchers use this compound to label biomolecules with fluorescent tags, allowing for enhanced imaging techniques in cellular studies and tracking biological processes in real-time.
  • Material Science: DBCO-NHS ester is applied in the modification of surfaces and materials, enhancing properties such as biocompatibility and functionality for applications in medical devices and tissue engineering.
  • Diagnostics: This chemical plays a crucial role in the development of assays and diagnostic tools, improving sensitivity and specificity in detecting diseases through innovative labeling techniques.

Citations